Evidence map›Paper›PMID 41890483›Full record

ArticleCureus2026

Rifaximin-Induced Rhabdomyolysis.

Samuel Acheampong, Chidimma Udoyeh, Prince Darko, Eunice K Omeludike

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samuel AcheampongInternal Medicine, Piedmont Athens Regional Medical Centre, Athens, USA.
Chidimma UdoyehInternal Medicine, Piedmont Athens Regional Medical Centre, Athens, USA.
Prince DarkoInternal Medicine, Piedmont Athens Regional Medical Centre, Athens, USA.
Eunice K OmeludikeInternal Medicine, Piedmont Athens Regional Medical Centre, Athens, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rifaximin is a non-absorbable oral antibiotic widely used for the management of traveler's diarrhea, hepatic encephalopathy, and irritable bowel syndrome diarrhea type. Although rifaximin is generally tolerated, rare cases of rhabdomyolysis have been reported, particularly in patients with cirrhosis with and without statin therapy. We reported a case of a 62-year-old male with a history of liver cirrhosis (ascites), hepatocellular carcinoma, and coronary artery disease (post coronary artery bypass grafting (CABG)) who presented with abdominal distension, generalized weakness, proximal muscle pain, and dark urine, with five years of atorvastatin medication without side effects. He was initiated on rifaximin (two weeks) for hepatic encephalopathy, along with lactulose, before experiencing proximal muscle pain and generalized weakness. This article will highlight our patient who developed rhabdomyolysis after initiating rifaximin with long-term use of statin, the trends of creatine kinase till resolution, and the treatment instituted.

Indexed as

acute kidney injurycreatine kinaserhabdomyolysisrifaximinstatin use

Identifiers

PMID41890483
PMCPMC13014114

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.