ArticleJournal of pharmacy & bioallied sciences
Analysis of Antimicrobial Utilization Pattern in Neonatal Intensive Care Unit: A Prospective Observational Study.
Article in Journal of pharmacy & bioallied sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: To analyze patterns of antimicrobial utilization and associated outcomes among neonates admitted to the neonatal intensive care unit (NICU) of a tertiary hospital in Madikeri, Karnataka, India. Materials and Methods: A prospective observational study was conducted over 18 months (January 2021-June 2023) in the NICU of Kodagu Institute of Medical Sciences. Data on demographics, diagnoses, antimicrobial prescriptions, dosing patterns, and outcomes were recorded. Rationality was assessed using the World Health Organization (WHO) prescribing indicators. Results: Of 1,072 neonates admitted, most received empirical antimicrobial therapy. Jaundice (40%) was the leading diagnosis, followed by respiratory distress syndrome (15%) and sepsis (12%). Cephalosporins (45%) and aminoglycosides (30%) were the most frequently prescribed classes, with amikacin-cefotaxime the predominant regimen. Over 80% of prescriptions were empirical, with limited culture-based modification. Adverse drug reactions occurred in 3% of neonates and were mild. Conclusion: Empirical, broad-spectrum antimicrobial use predominated, highlighting the need for enhanced culture-based therapy and stewardship interventions to limit resistance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.