Evidence map›Paper›PMID 41890324›Full record

ArticleAesthetic surgery journal. Open forum2026

The SIMPLE Technique for Unilateral Breast Reconstruction With Moderate Ptosis: Aiming for Durable Symmetry.

Alessandro Quattrini Li, Livio Colizzi, Elena Rossetti, Laura Coletti, Matteo Ghilli, Manuela Roncella

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Article in Aesthetic surgery journal. Open forum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alessandro Quattrini Li
Livio Colizzi
Elena Rossetti
Laura Coletti
Matteo Ghilli
Manuela Roncella

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unilateral breast reconstruction in patients with Grade 2 ptosis presents significant challenges in achieving long-term symmetry. Traditional approaches require contralateral symmetrization, increasing operative time, costs, and the risk of postoperative asymmetry because of progressive changes in the contralateral breast. This study evaluated the effectiveness of the SIMPLE technique (Symmetry in Moderate Ptosis for Long-Lasting Effectiveness) in prepectoral direct-to-implant (DTI) breast reconstruction for patients with Grade 2 ptosis. The goal was to restore the breast's original shape and volume, avoiding contralateral procedures. A retrospective review of 23 patients undergoing nipple-sparing mastectomy (NSM) followed by DTI prepectoral reconstruction using polyurethane-coated implants (Polytech Microthane Sublime Line) was conducted. The median follow-up was 603 days (range, 349-826 days). Inclusion criteria included a BMI <35.5 and no previous radiotherapy. Intraoperative confirmation of skin flap viability was assessed through indocyanine green angiography. Implants were strategically positioned to maintain symmetry, with special attention to alignment and preserving natural contours. All patients reported high satisfaction without the need for secondary procedures. Four minor complications were observed, along with 2 infections that required implant removal. No significant postoperative complications, such as implant exposure in the lower pole, implant displacement, or significant breast asymmetry requiring implant changes, were observed during the follow-up period, highlighting the technique's safety and effectiveness. The SIMPLE technique may represent a reliable option for breast reconstruction in selected patients with Grade 2 ptosis, reducing the need for contralateral symmetrization, surgical complexity and potentially supporting more durable symmetry, favorable aesthetics, and patient satisfaction.

Identifiers

PMID41890324
PMCPMC13014368

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.