ReviewFrontiers in plant science2026
Regulatory layers of robustness of CLAVATA-WUSCHEL feedback system in stem cell homeostasis.
Review in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Protein Phosphorylation: An Essential Role in Shoot Apical Meristem Homeostasis.Plants (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spatio-temporal regulation of gene expression and cellular behavior is critical for ensuring developmental robustness in all multicellular organisms. The mechanisms regulating robustness are often multilayered, with underlying processes occurring at different spatio-temporal scales. Pluripotent stem cells are maintained in SAMs despite periodic differentiation of stem-cell progeny into all above-ground organs, which together form much of the biomass on Earth. Shoot apical meristems (SAMs) are often exposed to variable growth conditions in nature; therefore, stem cell maintenance must be robust to withstand these changes. We focus our review on the mechanisms that regulate the robustness of the central CLAVATA (CLV)-WUSCHEL (WUS) feedback system, highlighting insights from new studies that integrate biological experiments with mathematical modeling. These studies have revealed the importance of WUS concentration-dependent transcription of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.