SynthesisFrontiers in aging neuroscience2026
Microglia associated research in depression: an exploratory trends analysis.
Synthesis in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Depression is a common and highly debilitating severe affective disorder. Relevant studies have indicated that microglia are closely associated with the progression of depression. This study conducts a bibliometric analysis on the research related to microglia in depression, aiming to clarify the evolution process, research hotspots, and future research directions in this field. Method: Relevant publications were retrieved from the Scopus and Web of Science databases. The software tools CiteSpace, VOSviewer, and Bibliometrix were employed for visual analysis. Results: A total of 2,305 publications on microglia in depression were included in the analysis. From 2001 to 2024, research in this area generally exhibited an upward trend. China had the largest number of research outcomes. Nantong University had the highest research output. Conclusion: This study provides a bibliometric perspective on microglia in depression. Research institutions from various countries have collaborated to advance this field. The neuroinflammation triggered by microglia has become an important theoretical framework for understanding the biological mechanisms of depression. Kynurenine pathway, NF-κB signaling, hypothalamus hypophysis adrenal system, and the gut microbiota may be the directions of future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.