Selective detection of Ochratoxin B in food by fluorescent sensor based on 2-mercapto-5-benzimidazole carboxylic acid-capped CdSe quantum dots.

Wenxin Chen, Jiahao Fu, Yaqi Liu, Yao Fan, Haiyan Fu, Yuanbin She

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Article in Food chemistry: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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6 authors.

Wenxin ChenState Key Laboratory of Green Chemical Synthesis and Conversion, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310032, PR China.

Jiahao FuState Key Laboratory of Green Chemical Synthesis and Conversion, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310032, PR China.

Yaqi LiuState Key Laboratory of Green Chemical Synthesis and Conversion, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310032, PR China.

Yao FanState Key Laboratory of Green Chemical Synthesis and Conversion, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310032, PR China.

Haiyan FuThe Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, PR China.

Yuanbin SheState Key Laboratory of Green Chemical Synthesis and Conversion, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310032, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ochratoxin B (OTB) that widely presented in food has significant cytotoxicity even at low concentration levels. Herein, a novel fluorescent sensor based on the 2-mercapto-5-benzimidazole carboxylic acid (MBI)-capped CdSe quantum dots (QDs) was established for the selective detection of OTB in food. Specifically, the synergistic effect of electrostatic interaction and intermolecular hydrogen bonds between MBI and OTB provided a direct and sensitive fluorescence signal that enables efficient recognition of OTB from other mycotoxins, even OTA with similar structures. Excellent linear detection performance for OTB is exhibited with a range from 0.037 ng/mL to 48.01 ng/mL and a detection limit of 0.016 ng/mL. Furthermore, our developed method exhibits good anti-interference stability against contaminants such as mycotoxins, inorganic salts and amino acids. Most importantly, the sensor demonstrates high sensitivity in real food samples with the recovery ranges from 96.51% to 104.7%, with an RSD of less than 2.67%.

Indexed as

Fluorescence sensorImidazolyl modificationOchratoxin B detectionQuantum dots

Identifiers

PMID41890170

DOI10.1016/j.fochx.2026.103770

PMCPMC13015747

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