ArticleFrontiers in surgery2026
Preoperative sarcopenia and its impact on postoperative complications in laparoscopic anti-reflux surgery: a clinical analysis.
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: To investigate the influence of sarcopenia on postoperative outcomes in gastroesophageal reflux disease patients undergoing concomitant laparoscopic hiatal hernia repair and laparoscopic fundoplication. Methods: Retrospective analysis was conducted on 69 patients who underwent laparoscopic hiatal hernia repair combined with laparoscopic fundoplication in the Department of Gastroenterology at the First Hospital of Hebei Medical University from September 2024 to May 2025. Skeletal muscle area at the L3 level was measured using abdominal CT scans within 10 days preoperatively to diagnose sarcopenia. Patients were divided into sarcopenia and non-sarcopenia groups. General clinical data, laboratory findings and postoperative complications were compared between the two groups to investigate the relationship between sarcopenia and postoperative complications following laparoscopic hiatal hernia repair combined with laparoscopic fundoplication. Results: Patients in the sarcopenia group were significantly older and exhibited lower BMI, lower preoperative scores on the gastroesophageal reflux disease questionnaire, and reduced acid exposure time percentages (all Conclusion: Our findings clearly indicate that while preoperative sarcopenia does not elevate the risk of postoperative dysphagia, it significantly delays the recovery of gastrointestinal function and leads to lower albumin levels following surgery in gastroesophageal reflux disease patients. This underscores the critical clinical importance of recognizing sarcopenia as a modifiable preoperative risk factor. We therefore propose the integration of routine sarcopenia screening into the preoperative assessment for gastroesophageal reflux disease patients. For those diagnosed with sarcopenia, a targeted prehabilitation protocol emphasizing nutritional support and physical training could be implemented to potentially enhance surgical tolerance and recovery outcomes. Future studies are warranted to validate the efficacy of such prehabilitation strategies and to further investigate the precise molecular mechanisms through which sarcopenia impedes postoperative recovery.
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