Evidence map›Paper›PMID 41890132›Full record

ArticlebioRxiv : the preprint server for biology2026

LGL-1 and the RhoGAP protein PAC-1 redundantly polarize the

Olga D Jarosińska, Amalia Riga, Hala Zahreddine Fahs, Joren M Woeltjes, Ruben Schmidt, Fathima S Refai, Suma Gopinadhan, Kristin C Gunsalus, Mike Boxem

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Olga D JarosińskaInstitute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.ORCID 0000-0002-2184-3993
Amalia RigaInstitute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.ORCID 0009-0001-3433-3650
Hala Zahreddine FahsCenter for Genomics and Systems Biology, New York University Abu Dhabi, United Arabic Emirates.ORCID 0000-0003-0720-2484
Joren M WoeltjesInstitute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.ORCID 0009-0002-1434-750X
Ruben SchmidtInstitute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.ORCID 0000-0001-9187-5424
Fathima S RefaiCenter for Genomics and Systems Biology, New York University Abu Dhabi, United Arabic Emirates.ORCID 0009-0005-5304-428X
Suma GopinadhanCenter for Genomics and Systems Biology, New York University Abu Dhabi, United Arabic Emirates.ORCID 0009-0004-8246-7559
Kristin C GunsalusCenter for Genomics and Systems Biology, New York University Abu Dhabi, United Arabic Emirates.ORCID 0000-0001-9769-4624
Mike BoxemInstitute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.ORCID 0000-0003-3966-4173

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Apical-basal polarity is essential for epithelial organization and function and is established by conserved cortical polarity proteins. However, the requirements for canonical polarity factors vary between tissues and organisms. For example, the basolateral protein lethal giant larvae (Lgl) is essential for epithelial polarity in

Indexed as

cell polarityembryogenesisepitheliaLglPAC-1RhoGAP19D

Identifiers

PMID41890132
PMCPMC13015541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.