Evidence map›Paper›PMID 41890031›Full record

ArticlebioRxiv : the preprint server for biology2026

SNED1 modulates ECM architecture and cell proliferation via LDV-binding integrins.

Dharma Pally, Leanna Leverton, Asantewaa Jones, Alexandra Naba

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Dharma PallyDepartment of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, 60612, U.S.A.
Leanna LevertonDepartment of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, 60612, U.S.A.
Asantewaa JonesDepartment of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, 60612, U.S.A.
Alexandra NabaDepartment of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, 60612, U.S.A.ORCID 0000-0002-4796-5614

Funding

Vascular Biology, Signaling and Therapeutics training programT32HL144459 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI KITAJEWSKI, JAN K., WARY, KISHORE K · 2019 to 2023
$1.6M
Mechanisms guiding the fibrillar assembly of SNED1 in the extracellular matrixR01GM148423 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Alexandra Naba · 2023 to 2026
$1.2M
NHLBI NIH HHS T32 HL144459NIGMS NIH HHS R01 GM148423
6 · The paper itself

Abstract

The extracellular matrix (ECM) is a complex scaffold of proteins that supports multicellular structures. Interactions between cells and the ECM via receptors, like integrins, govern cellular phenotypes (

Indexed as

Cell alignmentCell-derived matrixDecellularizationECM assemblyECM fibrils

Identifiers

PMID41890031
PMCPMC13015702

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.