Evidence map›Paper›PMID 41889982›Full record

ArticlebioRxiv : the preprint server for biology2026

Mapping Individualized Dual-Axis Network Topology in Focal Epilepsy: Divergent Alterations in System Integrity, Integration, and Clinical Correlates.

Qirui Zhang, Arielle Dascal, Sam S Javidi, Ankeeta Ankeeta, Michael R Sperling, Zhiqiang Zhang, Joseph I Tracy

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qirui ZhangFarber Institute for Neuroscience, Department of Neurology, Thomas Jefferson University; Philadelphia, PA, USA.ORCID 0000-0002-3520-9336
Arielle DascalBiomedical Engineering Department, McGill University, Montreal, QC, Canada.ORCID 0009-0009-3327-2313
Sam S JavidiFarber Institute for Neuroscience, Department of Neurology, Thomas Jefferson University; Philadelphia, PA, USA.ORCID 0000-0002-6653-1854
Ankeeta AnkeetaFarber Institute for Neuroscience, Department of Neurology, Thomas Jefferson University; Philadelphia, PA, USA.
Michael R SperlingFarber Institute for Neuroscience, Department of Neurology, Thomas Jefferson University; Philadelphia, PA, USA.ORCID 0000-0003-0708-6006
Zhiqiang ZhangDepartment of Diagnostic Radiology, Jinling Hospital, Medical School of Nanjing University; Nanjing, Jiangsu, P.R. China.ORCID 0000-0002-3993-7330
Joseph I TracyFarber Institute for Neuroscience, Department of Neurology, Thomas Jefferson University; Philadelphia, PA, USA.ORCID 0000-0001-5260-3290

Funding

Model Development for Prediction of Surgical Outcome in Temporal Lobe Epilepsy Patients: Incorporation of the Correlation between Post-Surgical Reorganization Phenotypes and Pre-Surgical DataR01NS112816 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI TRACY, JOSEPH I. · 2019 to 2023
$2.3M
NINDS NIH HHS R01 NS112816
6 · The paper itself

Abstract

Focal epilepsy is increasingly recognized as a disorder of distributed brain systems, yet characterizations of patient-specific alterations in network organization that are clinically meaningful remain limited. Here, we used resting-state functional MRI to introduce an overlap-permitting individualized network-estimation framework anchored to normative references to derive two complementary, system-level axes of topology: (1) network correspondence, indexing the expression of canonical networks and the fidelity of intrinsic system boundaries, and (2)

Indexed as

Focal epilepsiesIndividualized brain networksMacroscale brain organizationNetwork phenotypesNetwork topologySparse dictionary learning

Identifiers

PMID41889982
PMCPMC13015303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.