Evidence map›Paper›PMID 41889946›Full record

ArticlebioRxiv : the preprint server for biology2026

Dawei Sun, Daisy A Hoagland, Daniel Strebinger, Chenlei Hu, Benno C Orr, Shahinoor Begum, Giovanni Marrero, Jackson A Weir, Ruth A Franklin, Fei Chen

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dawei SunBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0003-1551-4349
Daisy A HoaglandDepartment of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.ORCID 0000-0002-6781-3079
Daniel StrebingerBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0001-8732-6414
Chenlei HuBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0009-0002-8145-5623
Benno C OrrBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0001-7231-4488
Shahinoor BegumDepartment of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.ORCID 0009-0003-3472-4605
Giovanni MarreroBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0003-1587-3624
Jackson A WeirBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0001-8741-1344
Ruth A FranklinDepartment of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.ORCID 0000-0002-6563-6187
Fei ChenBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0003-2308-3649

Funding

COVID19 Slide-seqR01HG010647 · NHGRI · BROAD INSTITUTE, INC. · PI Fei Chen, Evan Z Macosko · 2019 to 2026
$6.0M
Macrophage-mediated regulation of inflammation and tissue repairR35GM150816 · NIGMS · HARVARD MEDICAL SCHOOL · PI Ruth A Franklin · 2023 to 2026
$1.9M
Investigating Histone Acetylation Modulator Function in Alveolar Regeneration and Disease PathogenesisK99HL181185 · NHLBI · BROAD INSTITUTE, INC. · PI Dawei Sun · 2025 to 2026
$261k
NHGRI NIH HHS R01 HG010647NHLBI NIH HHS K99 HL181185NIGMS NIH HHS R35 GM150816
6 · The paper itself

Abstract

Effective alveolar repair after viral lung injury requires precise coordination of alveolar type 2 cell (AT2) proliferation and differentiation to restore lung function. To uncover causal regulators of this process in the native tissue environment, we developed SAGE (Stable Adeno-Associated Virus Genomic IntEgration), an engineered AAV system that enables high-throughput

Identifiers

PMID41889946
PMCPMC13015491

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.