Evidence map›Paper›PMID 41889938›Full record

ArticlebioRxiv : the preprint server for biology2026

Structural basis of receptor retro-translocation in peroxisomal protein import.

Nathaniel W M Dempsey, Laurie Wang, Ningjian Gao, Kangting Zhao, Jessica Cope, Eunyong Park

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Building peroxisomes: perspectives on plant peroxins.Biochemical Society transactions · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nathaniel W M DempseyDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.ORCID 0000-0002-0537-4197
Laurie WangDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
Ningjian GaoDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
Kangting ZhaoDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
Jessica CopeDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
Eunyong ParkDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.ORCID 0000-0003-2994-5174

Funding

THE MOLECULAR BASIS OF CELL FUNCTIONT32GM007232 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BILDER, DAVID, UNAL, ELCIN · 1985 to 2022
$36.4M
MOLECULAR BIOPHYSICS TRAINING GRANTT32GM008295 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HURLEY, JAMES H, WEMMER, DAVID E · 1989 to 2022
$8.1M
Molecular Biology Across Scales Training ProgramT32GM148378 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI David Bilder, Elcin Unal · 2023 to 2026
$7.3M
Molecular Mechanisms of Mitochondrial BiogenesisR01GM147628 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Eunyong Park · 2023 to 2026
$1.3M
NIGMS NIH HHS R01 GM147628NIGMS NIH HHS T32 GM007232NIGMS NIH HHS T32 GM008295NIGMS NIH HHS T32 GM148378
6 · The paper itself

Abstract

Peroxisomes import all matrix proteins post-translationally from the cytosol, a process that requires recycling of cargo receptors across the peroxisomal membrane. The membrane-embedded ubiquitin ligase, composed of Pex2, Pex10, and Pex12, is central to this process, but its mechanism remains unclear. Here we determined cryo-electron microscopy structures of the

Identifiers

PMID41889938
PMCPMC13015374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.