ArticlebioRxiv : the preprint server for biology2026
Therapeutic scheduling of WEE1 inhibition preserves T cell function and promotes immune control of HPV
Abstract readPreprint
In one paragraph
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors.
Ying LiuDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Zhiheng ZhangDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Yanshan TaoDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Lovely RahgavDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Sophie Gray-GaillardDepartment of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0002-4884-5956
Yasser HussainiTranslational Therapeutics and Human Biology Divisions, Fred Hutchinson Cancer Center, Seattle, WA.
Meijie PanDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0009-0006-9562-0422
Justine ShamberDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Jeff KwakTranslational Therapeutics and Human Biology Divisions, Fred Hutchinson Cancer Center, Seattle, WA.
Simone L ParkDepartment of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0003-1507-0864
Jessica CramerDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Regina StoltzDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Joseph PatriaDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Jherek SwangerTranslational Therapeutics and Human Biology Divisions, Fred Hutchinson Cancer Center, Seattle, WA.
Kathryn LiuDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Malay Kumar SannigrahiDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
A McGarry HoughtonTranslational Therapeutics and Human Biology Divisions, Fred Hutchinson Cancer Center, Seattle, WA.ORCID 0000-0002-8970-3137
Cristina P RodriguezDepartment of Medicine, University of Washington, Seattle, WA.
Ryan M CareyDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Robert BrodyDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0001-6639-8830
Karthik RajasekaranDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0003-2148-1643
Gregory WeinsteinDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Gerald P LinetteCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0001-6147-6115
Beatriz M CarrenoCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0002-8123-2035
Mark M PainterDepartment of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0002-0180-2748
E John WherryDepartment of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0003-0477-1956
Bruce ClurmanTranslational Therapeutics and Human Biology Divisions, Fred Hutchinson Cancer Center, Seattle, WA.ORCID 0000-0002-5835-9361
Devraj BasuDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Ahmed DiabDepartment of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0001-6626-7013
Funding
Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4MVisualizing EBV and HCMV DNA Dynamics During InfectionP01CA022443 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Paul F. Lambert · 1985 to 2026
$53.1MTRANSGENIC AND CHIMERIC MOUSE COREP30DK050306 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI GARY D. WU · 1997 to 2026
$32.5MExploiting differences in HPV oncoprotein function among oropharyngeal cancers to personalize therapyR01DE034056 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI Devraj Basu · 2024 to 2026
$1.7MTargeting the DNA Damage Response in HPV+ Head and Neck CancerR00DE030194 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI Ahmed Mohamed Diab · 2024 to 2026
$747kTargeting the DNA Damage Response in HPV+ Head and Neck CancerK99DE030194 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI DIAB, AHMED MOHAMED · 2021 to 2022
$325kNCI NIH HHS P01 CA022443NCI NIH HHS P30 CA015704NIDCR NIH HHS K99 DE030194NIDCR NIH HHS R00 DE030194NIDCR NIH HHS R01 DE034056NIDDK NIH HHS P30 DK050306
Abstract
Human papillomavirus-associated oropharyngeal squamous cell carcinoma (HPV
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LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.