Evidence map›Paper›PMID 41889851›Full record

ArticlebioRxiv : the preprint server for biology2026

Using image classifiers to predict CMT2A disease-relevant mitochondrial motility phenotypes in iPSC motor neurons.

Leo Epstein, Adam C Weiner, Bria L Macklin, Kaitlin R Kelly, Bruce R Conklin, Barbara E Engelhardt

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Leo EpsteinGladstone Institutes, Institute of Data Science and Biotechnology, San Francisco, 94158, USA.ORCID 0009-0009-0607-854X
Adam C WeinerGladstone Institutes, Institute of Data Science and Biotechnology, San Francisco, 94158, USA.ORCID 0000-0002-5968-3606
Bria L MacklinGladstone Institutes, Institute of Data Science and Biotechnology, San Francisco, 94158, USA.ORCID 0000-0002-3744-6431
Kaitlin R KellyGladstone Institutes, Institute of Data Science and Biotechnology, San Francisco, 94158, USA.ORCID 0009-0000-7165-5651
Bruce R ConklinGladstone Institutes, Institute of Data Science and Biotechnology, San Francisco, 94158, USA.ORCID 0000-0003-1463-6061
Barbara E EngelhardtGladstone Institutes, Institute of Data Science and Biotechnology, San Francisco, 94158, USA.ORCID 0000-0002-6139-7334

Funding

A kinetic framework to map the genetic determinants of alternative RNA isoform expressionR01HG012967 · NHGRI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Barbara Engelhardt, Athma A Pai · 2023 to 2026
$3.0M
Methods to build and annotate tissue atlases using spatial genomic dataR01HG013736 · NHGRI · J. DAVID GLADSTONE INSTITUTES · PI Barbara Engelhardt · 2024 to 2026
$2.5M
Allele-specific inactivation for dominant negative NEFL MutationsR01NS119678 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JUDGE, LUKE M · 2021 to 2025
$1.9M
C9orf72 frontotemporal dementia (FTD) and amyotrophic lateral sclerosis(ALS): using patient cells and CRISPR to reveal therapeutic approachesR01AG072052 · NIA · J. DAVID GLADSTONE INSTITUTES · PI CONKLIN, BRUCE R · 2024 to 2025
$1.4M
NHGRI NIH HHS R01 HG012967NHGRI NIH HHS R01 HG013736NIA NIH HHS R01 AG072052NINDS NIH HHS R01 NS119678
6 · The paper itself

Abstract

Charcot-Marie-Tooth disease type 2A (CMT2A) is a genetic disease characterized by autosomal dominant

Identifiers

PMID41889851
PMCPMC13015418

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.