Evidence map›Paper›PMID 41889818›Full record

ArticlebioRxiv : the preprint server for biology2026

YdbL directly modulates YdbH-YnbE bridge formation to maintain

Clare De'Ath, Sujeet Kumar, Sachi Chhibber, Benjamin F Cooper, Emilia K Taylor, Emily Jones, Thomas Lanyon-Hogg, Jani R Bolla, Christina Redfield, Natividad Ruiz and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Clare De'AthSir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK.ORCID 0000-0002-6293-2159
Sujeet KumarDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-8207-4358
Sachi ChhibberDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, USA.
Benjamin F CooperSir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK.ORCID 0000-0002-4023-9011
Emilia K TaylorSir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK.ORCID 0000-0001-7787-0408
Emily JonesSir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK.
Thomas Lanyon-HoggDepartment of Pharmacology, University of Oxford, Oxford, OX1 3QT, UK.ORCID 0000-0002-7092-8096
Jani R BollaDepartment of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.ORCID 0000-0003-4346-182X
Christina RedfieldDepartment of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.ORCID 0000-0001-7297-7708
Natividad RuizDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-6369-2206
Georgia L IsomSir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK.ORCID 0000-0001-9023-705X

Funding

Envelope biogenesis in Gram-negative bacteriaR35GM153349 · NIGMS · OHIO STATE UNIVERSITY · PI Natividad Ruiz · 2024 to 2026
$1.1M
NIGMS NIH HHS R35 GM153349Wellcome Trust
6 · The paper itself

Abstract

Gram-negative bacteria pose a threat to global healthcare mainly because their outer membrane (OM) provides an intrinsic barrier to many antimicrobials. Key to this barrier function is the asymmetric structure of the OM, with phospholipids constituting the inner leaflet and lipopolysaccharides the outer leaflet. Although the mechanism of phospholipid transport between the inner membrane (IM) and OM remains poorly understood, recent studies implicate TamB, YhdP, and YdbH as functionally redundant proteins mediating this process in

Identifiers

PMID41889818
PMCPMC13015361

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.