ArticlebioRxiv : the preprint server for biology2026
Coordinated topoisomerase function shapes the fluoroquinolone response of
Andrew Terrebonne, Caitlynn Diggs, Scot P Ouellette, Leiqiong Gao, Yuk-Ching Tse-Dinh, Li Shen
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
6 authors.
Andrew TerrebonneDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112.
Caitlynn DiggsDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112.
Scot P OuelletteDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, USA.ORCID 0000-0002-3721-6839 Leiqiong GaoDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112.
Yuk-Ching Tse-DinhBiomolecular Sciences Institute, Department of Chemistry and Biochemistry, Florida International University, Miami, FL 33199, USA.
Li ShenDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112.ORCID 0000-0001-9869-7317 Funding
LSUHSC-New Orleans Postbaccalaureate Research Education Program in Biomedical SciencesR25GM148309 · NIGMS · LSU HEALTH SCIENCES CENTER · PI HARRISON-BERNARD, LISA M. · 2023 to 2024
$453kCRISPR interference of essential stage-specific gene function in Chlamydia trachomatisR21AI175651 · NIAID · LSU HEALTH SCIENCES CENTER · PI SHEN, LI · 2023 to 2024
$429kNIAID NIH HHS R21 AI175651NIGMS NIH HHS R25 GM148309
6 · The paper itselfAbstract
DNA supercoiling is essential for the developmental cycle of
Indexed as
antibiotic toleranceChlamydia trachomatisDNA gyraseDNA replicationDNA supercoilingfluoroquinolone moxifloxacinpersistent formstress adaptationTopAtranscription
Identifiers
PMID41889814
PMCPMC13015337
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