ArticlebioRxiv : the preprint server for biology2026
Selective regulation of transsynaptic alignment and postsynaptic assembly by a novel NCAM family synaptic adhesion molecule.
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Synapse formation underlies the organization of neurons into functional circuits during brain development and requires precise alignment and maturation of pre- and postsynaptic compartments. Many synaptogenic adhesion molecules have been identified that drive target recognition and sustained adhesion between appropriate synaptic partners. Yet the degree to which individual molecules serve selective functions in distinct aspects of synapse formation and maturation remains poorly understood. In particular, how exquisite nanoalignment of pre- and postsynaptic specializations flows from micron-scale adhesive interactions between synaptic partners remains a key unanswered question. Here we shed new light on this question by establishing a specialized set of synaptic functions for
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