Evidence map›Paper›PMID 41889736›Full record

ArticleJACS Au2026

Manasik Gumah Adam Ali, Venetia Psomiadou, Marta Tiemblo Martín, Dimitra Lamprinaki, Ferran Nieto-Fabregat, Klaudia Sobczak, Matthew S Macauley, June Ereño-Orbea, Cristina De Castro, Alba Silipo and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Manasik Gumah Adam AliQuadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, United Kingdom.
Venetia PsomiadouSynthetic organic chemistry, Institute for molecules and materials, Radboud University, Heyendaalseweg 135, Nijmegen 6525 AJ, The Netherlands.
Marta Tiemblo MartínDepartment of Chemical Sciences, University of Naples Federico II, Naples 80131, Italy.
Dimitra LamprinakiQuadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, United Kingdom.
Ferran Nieto-FabregatDepartment of Chemical Sciences, University of Naples Federico II, Naples 80131, Italy.ORCID https://orcid.org/0000-0001-9847-3030
Klaudia SobczakChemical Glycobiology Lab, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 800, Derio, Bizkaia 48160, Spain.
Matthew S MacauleyDepartments of Chemistry, and Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta AB T6G 2E1, Canada.ORCID https://orcid.org/0000-0003-4579-1048
June Ereño-OrbeaChemical Glycobiology Lab, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 800, Derio, Bizkaia 48160, Spain.ORCID https://orcid.org/0000-0002-5076-2105
Cristina De CastroDepartment of Chemical Sciences, University of Naples Federico II, Naples 80131, Italy.ORCID https://orcid.org/0000-0002-5147-1756
Alba SilipoDepartment of Chemical Sciences, University of Naples Federico II, Naples 80131, Italy.ORCID https://orcid.org/0000-0002-5394-6532
Thomas J BoltjeSynthetic organic chemistry, Institute for molecules and materials, Radboud University, Heyendaalseweg 135, Nijmegen 6525 AJ, The Netherlands.
Nathalie JugeQuadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, United Kingdom.ORCID https://orcid.org/0000-0001-8515-1315

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sialic acid-binding immunoglobulin-like lectins (Siglecs) are key immune receptors that bind to cell surface sialic acids, leading to modulation of the immune system. Interrupting the Siglec-sialoglycan binding in cancer has been proposed as a potential antitumor response strategy. We previously showed that colon-cancer-associated

Indexed as

bioorthogonal chemistrycolorectal cancerFusobacterium nucleatumlipopolysaccharidesialic acidSiglec-7

Identifiers

PMID41889736
PMCPMC13014188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.