SynthesisFrontiers in nutrition2026
Preoperative carbohydrate loading: evolution, trends, and future directions.
Synthesis in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Preoperative carbohydrate loading (PCL) counteracts the catabolic effects of fasting by alleviating insulin resistance and maintaining metabolic homeostasis. Despite its widespread use in clinical settings, there is no existing literature examining past achievements and breakthroughs in this area. The purpose of this study is to characterize its publication patterns, academic influence, research trends, and recent developments worldwide. Methods: The Web of Science Core Collection and PubMed were searched for documents published from the time the databases began to include relevant articles to March 27, 2025. Using VOSviewer, Citespace, and SciExplorer, a cross-sectional bibliometric analysis was conducted to extract and calculate evaluative indices. Publications were categorized by country, institution, author, journal, highly cited papers, and keywords. The variables were compared in terms of publication and academic influence, which also included citation count, journal impact factor, total link strength, collaboration metrics, and impact relative to the global community. Results: There were 269 publications, involving the contributions of 1,478 authors affiliated with 439 institutions across 38 countries/regions, and 141 clinical trials. China has the highest number of publications, albeit with limited collaboration, while England exhibits the highest centrality and a dense international cooperation network. The top ten journals in terms of publications are mostly high-quality journals. The author who has made the most outstanding and irreplaceable contribution is Olle Ljungqvist. Institutional cooperation is primarily geographically limited, with few links to transnational cooperation. We determine that "metabolic responses," "recovery and clinical outcomes," "preoperative management," and "research techniques" are the most discussed research topics and identify four research frontiers and directions. Conclusion: Research on PCL has transitioned from early physiological validation to widespread clinical integration within ERAS protocols. The bibliometric patterns indicate that, despite substantial progress in understanding metabolic responses and perioperative management, key gaps remain in translating PCL evidence into personalized, harmonized, and technologically supported clinical nutrition practices. Clinicians and dietitians should prioritize tailoring PCL strategies to patient-specific factors, while integrating harmonized outcomes and technology to better assess individual responses. Besides, multidisciplinary collaboration between surgeons, anesthetists, and dietitians is essential to ensure consistent implementation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.