Evidence map›Paper›PMID 41889453›Full record

ArticleOpen forum infectious diseases2026

Penicillin Allergy Labels and High-risk Antibiotic Prescribing Among Incarcerated Individuals Receiving Antibiotics Across Four US Carceral Systems.

Samuel Wilk, Kap Sum Foong, Rachel Tam, Larissa Grigoryan, Lindsay Taylor, Lara B Strick, Rachel Sandler Silva, Alysse Wurcel

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Samuel WilkTufts University School of Medicine, Boston, Massachusetts, USA.ORCID https://orcid.org/0009-0000-5475-0331
Kap Sum FoongDivision of Geographic Medicine and Infectious Diseases, Department of Medicine, Tufts Medical Center,Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-6259-0032
Rachel TamSection of General Internal Medicine, Boston Medical Center, Boston, Massachusetts, USA.ORCID https://orcid.org/0009-0006-9200-4237
Larissa GrigoryanDepartment of Family and Community Medicine, Baylor College of Medicine, Houston, Texas, USA.
Lindsay TaylorDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0002-6622-4379
Lara B StrickDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0009-0007-3300-2968
Rachel Sandler SilvaDepartment of Medicine, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA.ORCID https://orcid.org/0000-0002-2779-941X
Alysse WurcelSection of General Internal Medicine, Boston Medical Center, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-8255-8387

Funding

CTSA K12 Program at Tufts UniversityK12TR004384 · NCATS · TUFTS UNIVERSITY BOSTON · PI Karen Freund, Lesley Ann Inker · 2023 to 2026
$6.1M
NCATS NIH HHS K12 TR004384
6 · The paper itself

Abstract

Background: Optimization of antibiotic prescribing is critical to reducing antimicrobial resistance, yet antimicrobial stewardship programs remain relatively uncommon in carceral settings. Despite the disproportionate health burden faced by incarcerated populations, limited data exist on the prevalence of penicillin allergy labels (PALs) in these sites. This study examined the carceral systems in 4 states (Maine, New Hampshire, Washington, and Minnesota's Hennepin County Jail) and determined the prevalence of PALs, their demographic predictors, and the relationship between PALs and the prescription of high-risk antibiotics for Methods: We conducted a retrospective cohort study using the de-identified data from 4 carceral systems, restricted to incarcerated people who received at least 1 antibiotic prescription between 2020 and 2023. We performed univariate and multivariate logistic regression analyses, adjusting for age, sex, race, and ethnicity. We reported adjusted odds ratios (aORs) with 95% confidence intervals (CIs). Results: The final study cohort consisted of 10 603 individuals, with a PAL prevalence of 10.2%. Individuals with PALs were less likely to be male (aOR, 0.462; 95% CI, 0.355-0.601) or Hispanic (aOR, 0.500; 95% CI, 0.272-0.920) and more likely to be White non-Hispanic (aOR, 1.458; 95% CI, 1.075-1.978), or American Indian/Alaska Native (aOR, 2.466; 95% CI, 1.641-3.707). PALs were significantly associated with increased odds of receiving high-risk antibiotics for CDI (aOR, 2.412; 95% CI, 1.893-3.074). Conclusions: Our findings highlight the need for targeted antimicrobial stewardship and penicillin allergy de-labeling efforts among incarcerated individuals needing antibiotics.

Indexed as

antimicrobial stewardshipcarceral settingincarcerated populationspenicillin allergypenicillin allergy delabeling

Identifiers

PMID41889453
PMCPMC13014467

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.