Evidence map›Paper›PMID 41889379›Full record

ArticleHemodialysis international. International Symposium on Home Hemodialysis2026

Hemodiafiltration at Home: A Single Centre Experience Reviewing Safety, Efficacy, and Implementation.

Maddison Taylor, Yeoungjee Cho, Rodney Brickle, Lisa Ditterich, Sheree Sodeman, Diana Leary, Carolyn van Eps

Abstract read
In one paragraph

Article in Hemodialysis international. International Symposium on Home Hemodialysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maddison TaylorDepartment of Kidney and Transplant Services, Division of Medicine, Princess Alexandra Hospital, Brisbane, Australia.ORCID https://orcid.org/0009-0005-2670-1184
Yeoungjee ChoDepartment of Kidney and Transplant Services, Division of Medicine, Princess Alexandra Hospital, Brisbane, Australia.ORCID https://orcid.org/0000-0002-3502-9837
Rodney BrickleDepartment of Kidney and Transplant Services, Division of Medicine, Princess Alexandra Hospital, Brisbane, Australia.
Lisa DitterichDepartment of Kidney and Transplant Services, Division of Medicine, Princess Alexandra Hospital, Brisbane, Australia.
Sheree SodemanDepartment of Kidney and Transplant Services, Division of Medicine, Princess Alexandra Hospital, Brisbane, Australia.
Diana LearyDepartment of Kidney and Transplant Services, Division of Medicine, Princess Alexandra Hospital, Brisbane, Australia.
Carolyn van EpsDepartment of Kidney and Transplant Services, Division of Medicine, Princess Alexandra Hospital, Brisbane, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with kidney failure receiving dialysis are at an increased risk of cardiovascular events. Hemodiafiltration (HDF) has been shown to decrease cardiovascular mortality. Due to concerns around technical challenges and the need to achieve ultra-pure water standards, HDF is not readily available for those receiving hemodialysis at home. This study was conducted to describe the process and outcomes in implementing a home HDF program.

methodsPatients who received home HDF training between 2014 and 2024 at the Princess Alexandra Hospital, Australia were included. The primary outcome was the proportion of patients who successfully completed training for HDF at home. Outcomes related to training duration, water, and clinical outcomes including hospitalizations, transfer to facility-based hemodialysis were analyzed descriptively.

findingsIn total, 42 patients (67% male, mean age 51.1 ± 12.8 years) undertook HDF therapy at home. About 39 patients commenced HDF training with a 100% training success rate, and 3 patients were supported by nursing-assisted HDF therapy at home. Median training duration was 61 days, which was longer for patients who were new to starting home dialysis (126 days), compared to those who converted from home hemodialysis to HDF (14.5 days, p < 0.05). HDF prescriptions were highly variable (mean treatment hours 15.7 ± 4.9 h/week). The median time of home HDF treatment was 17.5 months (interquartile range IQR 9.9-31). In the first 6 months after starting HDF at home, there were no hospitalizations due to dialysis-related technical issues including water-related problems. Three patients (7%) transitioned to facility-based hemodialysis. DISCUSSION: HDF at home is a safe therapy for patients who are considered to receive hemodialysis at home, offering increased flexibility and personalized prescriptions.

Indexed as

HemodiafiltrationHemodialysis, HomeKidney Failure, ChronicAdultAgedAustraliaFemaleHumansMaleMiddle Ageddialysishemodiafiltrationhome hemodialysisoutcomestrainingwater quality

Identifiers

PMID41889379
PMCPMC13350406

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.