Evidence map›Paper›PMID 41889270›Full record

ArticleLasers in surgery and medicine2026

Effects of Dual Wavelength Photobiomodulation on Osseointegration in Grafted Areas.

Lucas de Sousa Goulart Pereira, Julia Raulino Lima, Elcio Marcantonio, Priscilla Barbosa Ferreira Soares, Suzane Cristina Pigossi, Guilherme José Pimentel Lopes de Oliveira

Abstract read
In one paragraph

Article in Lasers in surgery and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lucas de Sousa Goulart PereiraDepartment of Periodontology, School of Dentistry, Federal University of Uberlândia-UFU, Uberlândia, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0002-1447-6611
Julia Raulino LimaDepartment of Periodontology, School of Dentistry, Federal University of Uberlândia-UFU, Uberlândia, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0002-6824-4904
Elcio MarcantonioDepartment of Diagnosis and Surgery, Araraquara School of Dentistry, Universidade Estadual Paulista (FOAr-UNESP), Araraquara, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-1294-2305
Priscilla Barbosa Ferreira SoaresDepartment of Periodontology, School of Dentistry, Federal University of Uberlândia-UFU, Uberlândia, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0002-4492-8957
Suzane Cristina PigossiDepartment of Periodontology, School of Dentistry, Federal University of Uberlândia-UFU, Uberlândia, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0001-7067-6119
Guilherme José Pimentel Lopes de OliveiraDepartment of Periodontology, School of Dentistry, Federal University of Uberlândia-UFU, Uberlândia, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0001-8778-0115

Funding

CNPqFAPEMIG, Fundação de amparo a pesquisa de Minas Gerais (Grants INCT Saúde Oral e Odontologia 406840/2022-9FAPEMIG, Fundação de amparo a pesquisa de Minas Gerais (Grants INCT Saúde Oral e Odontologia APQ-02211-21National Council for Scientific and Technological Development
6 · The paper itself

Abstract

objectiveThis study evaluated the effects of dual-wavelength photobiomodulation (PBMT) (infrared and red laser) on osseointegration and bone structure in areas grafted with deproteinized bovine bone (DBB).

methodsSixty-four rats were randomly distributed into four groups. The groups were divided according to the irradiation protocol applied: CTR-Implants not submitted to PBMT; IRL-Implants treated with infrared PBMT; RL-Implants treated with red PBMT; IRL/RL-Implants treated with red and infrared PBMT. The animals underwent grafting procedures on the tibias, and 60 days later, the implants were installed. After the implant placement, PBMT was performed in the PBMT groups through the application of 4 J around the implants. After 15 and 45 days, the animals were euthanized (n = 8). Analyses were performed on the amount of mineralized tissues around the implants (BV/TV%), bone tissue microstructure (thickness, space and number of trabeculae-Tb.Th; Tb.Sp, and Tb.N), and osseointegration (bone/implant contact-%BIC and Bone between the threads-%BBT).

resultsThe IRL group presented higher values of BV/TV%, while the RL group presented higher values of Tb.N when compared with the CTR group at 45 days (p < 0.05). The IRL/RL group presented higher values of BV/TV% and Tb.N when compared with the CTR group at 45 days (p < 0.05). Although no statistical differences were found, the IRL/RL group presented higher %BIC and %BBT.

conclusionIt can be concluded that the combination of red and infrared lasers does not improve the osseointegration of the implants installed in DBB-grafted areas of rat tibiae.

Indexed as

Bone TransplantationLow-Level Light TherapyOsseointegrationTibiaAnimalsCattleInfrared RaysMaleRandom AllocationRatsRats, WistarRed Lightbone substitutesosseointegrationphotobiomodulation

Identifiers

PMID41889270
PMCPMC13269856

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.