Evidence map›Paper›PMID 41889257›Full record

ArticleJournal of applied clinical medical physics2026

Interpretable LightGBM model with SHAP analysis predicts non-excellent response to initial radioiodine therapy in differentiated thyroid carcinoma.

Zhaoxia Luo, Yangyang Lei, Qing Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied clinical medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhaoxia LuoDepartment of Nuclear Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Yangyang LeiDepartment of Nuclear Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Qing ZhangDepartment of Nuclear Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.

Funding

Key Project of Natural Science Foundation of Jiangxi Province 20232ACB206026National Natural Science Foundation of China 82260356National Natural Science Foundation of China 8226070308
6 · The paper itself

Abstract

purposeTo identify independent determinants influencing therapeutic outcomes of initial radioactive iodine ( MATERIALS AND

methodsA retrospective cohort of 950 treatment-naïve DTC patients undergoing primary

resultsMultivariable analysis demonstrated age,

conclusionThe developed LightGBM framework precisely predicts primary

Indexed as

Iodine RadioisotopesThyroid NeoplasmsAdultAgedBoosting Machine Learning AlgorithmsFemaleFollow-Up StudiesHumansMachine LearningMaleMiddle AgedPredictive Learning ModelsPrognosisRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRandom ForestIodine Radioisotopesdifferentiated thyroid carcinomamachine learningpredictive modelingradioiodine therapySHAP interpretability

Identifiers

PMID41889257
PMCPMC13140707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.