Evidence map›Paper›PMID 41888768›Full record

Trial reportBMC complementary medicine and therapies2026

Perioperative transcutaneous electrical acupoint stimulation at pericardium 6 reduces postoperative nausea and vomiting after tympanoplasty patients: a randomized controlled study.

Lu Luo, Yaojing Fu, Shuangshuang Li, Jie Jia

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC complementary medicine and therapies, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Lu Luo *Department of Anesthesiology, EYE & ENT Hospital of Fudan University, 2600 Jiangyue Road, Pujin Street, Shanghai, Minhang, 200032, China.
Yaojing Fu *Department of Anesthesiology, EYE & ENT Hospital of Fudan University, 2600 Jiangyue Road, Pujin Street, Shanghai, Minhang, 200032, China.
Shuangshuang LiDepartment of Anesthesiology, EYE & ENT Hospital of Fudan University, 2600 Jiangyue Road, Pujin Street, Shanghai, Minhang, 200032, China. lishuangshuang@eentanesthesia.com.
Jie JiaDepartment of Anesthesiology, EYE & ENT Hospital of Fudan University, 2600 Jiangyue Road, Pujin Street, Shanghai, Minhang, 200032, China. jiajie@eentanesthesia.com.

Funding

National Natural Science Foundation of China 82201375
6 · The paper itself

Abstract

backgroundPostoperative nausea and vomiting (PONV) remains a prevalent and distressing complication following tympanoplasty. Stimulation of the Pericardium 6 (PC6) acupoint has emerged as a promising non-pharmacological strategy for PONV management in various surgical procedures. Therefore, this study aimed to evaluate the efficacy of transcutaneous electrical acupoint stimulation (TEAS) at PC6 as an adjunct to standard antiemetic prophylaxis in patients undergoing tympanoplasty.

methodsIn this prospective, single-blind, randomized, parallel-group trial, we enrolled 277 patients (aged 18–65 years; ASA physical status I–II) scheduled for tympanoplasty. Participants were randomized to receive either active transcutaneous electrical acupoint stimulation (TEAS group, n = 138) or sham TEAS (Sham-TEAS group, n = 139). The primary endpoint was the incidence of PONV within 48 h postoperatively. Secondary endpoints included the rate of complete response (CR), the severity of PONV, the requirement for rescue antiemetics, postoperative pain scores, and the incidence of other adverse events.

resultsCompared with the Sham group, the TEAS group exhibited a significantly lower incidence of nausea (17.4% vs. 39.1%, p < 0.01) and vomiting (6.5% vs. 19.4%, p < 0.01). Conversely, the rate of complete response (CR) was significantly higher in the TEAS group than in the Sham group (81.6% vs. 59.7%, p < 0.01). No significant intergroup differences were observed regarding recovery parameters or other adverse events.

conclusionsPerioperative PC6 TEAS serves as a safe and efficacious adjunctive strategy for preventing PONV in patients undergoing tympanoplasty. Our findings support the integration of TEAS into multimodal antiemetic protocols to optimize perioperative care for this high-risk population.

Indexed as

Acupuncture PointsPostoperative Nausea and VomitingTranscutaneous Electric Nerve StimulationTympanoplastyAdolescentAdultAgedFemaleHumansMaleMiddle AgedPericardiumProspective StudiesSingle-Blind MethodYoung AdultPostoperative nausea and vomitingTranscutaneous electrical stimulation, PC6.Tympanoplasty

Identifiers

PMID41888768
PMCPMC13141521

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.