ArticleBMC infectious diseases2026
Comparative analysis of parenchymal and extraparenchymal neurocysticercosis: a 10-year experience from northern Thailand.
Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Neuroimaging Features of an Experimental Model of Extraparenchymal Neurocysticercosis.Acta parasitologica · 2026Article
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7 authors.
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Abstract
backgroundNeurocysticercosis (NCC) is a leading cause of epilepsy and neurological morbidity in endemic regions. This study compares clinical characteristics, treatment, and outcomes between parenchymal and extraparenchymal NCC in northern Thailand.
methodsA retrospective cohort of 106 adult NCC patients (2015–2024) was reviewed at Chiang Mai University. Patients were categorized based on neuroimaging. Clinical data, treatment regimens, and functional outcomes (using modified Rankin Scale) were assessed at baseline, discharge, and 3, 6, and 12 months.
resultsOf 106 patients, 84 (79.2%) had parenchymal and 22 (20.8%) had extraparenchymal NCC. Seizures were more common in parenchymal cases, while sensory deficits and hydrocephalus predominated in extraparenchymal cases. Surgical intervention was significantly more frequent in extraparenchymal NCC (86.4% vs. 4.8%, P < 0.001). Despite overall improvement, extraparenchymal cases had worse outcomes at all time points. Corticosteroids did not improve long-term function and were linked to more adverse events.
conclusionsParenchymal and extraparenchymal NCC have distinct clinical patterns and outcomes. Extraparenchymal NCC is more severe, frequently requiring surgery and resulting in greater disability. Corticosteroid use showed no association with long-term outcomes, highlighting the need for early diagnosis and tailored treatment strategies.
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