Evidence map›Paper›PMID 41888594›Full record

ArticleNature microbiology2026

A global-scale assessment of zoonotic virus diversity and spillover potential in urban-adapted mammal species.

Xuemin Wei, Hongfeng Li, Zheng Y X Huang, Shuo Li, Yuhao Wang, Jie Lan, Li Hu, Yang Li, Daniel J Becker, Fuwen Wei and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xuemin Wei *Department of Microbiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Hongfeng Li *Department of Microbiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Zheng Y X Huang *Department of Zoology, School of Life Sciences, Nanjing Forestry University, Nanjing, Jiangsu, China.
Shuo LiDepartment of Microbiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Yuhao WangDepartment of Microbiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Jie LanDepartment of Microbiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Li HuDepartment of Microbiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Yang LiCAS Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Daniel J BeckerSchool of Biological Sciences, University of Oklahoma, Norman, OK, USA. danbeck@ou.edu.ORCID http://orcid.org/0000-0003-4315-8628
Fuwen WeiCAS Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. weifw@ioz.ac.cn.ORCID http://orcid.org/0000-0002-5233-1288
Yifei XuDepartment of Microbiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China. yifei.xu@sdu.edu.cn.ORCID http://orcid.org/0000-0003-1969-2484

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The repeated emergence of pandemic viruses underscores the linkages between land-use change and wildlife disease, and urban-adapted wildlife are of special interest due to their close proximity to humans. However, viral diversity within urban-adapted species and their zoonotic potential remain largely unexplored. Here we compiled a dataset of documented records spanning from 1574 to 2023 on red foxes, raccoons, raccoon dogs, masked palm civets, European hedgehogs, European shrews, wild boars and their viruses, covering 116 countries. These urban-adapted mammals host 286 virus species spanning 24 orders and 38 families, 14 of which are potentially high risk for human infection. Raccoon dogs had increased viral positivity in urban habitats compared to raccoons, wild boars and red foxes. Many viruses in urban-adapted species were phylogenetically related to those found in humans, and our data suggest possible viral spillback. These results highlight zoonotic risks associated with urban-adapted species and suggest enhanced surveillance to mitigate future outbreaks.

Indexed as

MammalsViral ZoonosesVirusesZoonosesAnimalsAnimals, WildBiodiversityCitiesEcosystemGenetic VariationHumansPhylogeny

Identifiers

PMID41888594

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.