Evidence map›Paper›PMID 41888477›Full record

ArticlePediatric nephrology (Berlin, Germany)2026

Pediatric renal abscess: a 12-year single-center retrospective analysis.

Jian-Qun Guo, Mei-Hao Gao, Yi-Jiao Ma, Shi-Lei Jia, Xiao-Jie Gao, Jun Li

Abstract read
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jian-Qun Guo *Division of Pediatric Nephrology, Shenzhen Children's Hospital, Shenzhen, Guangdong Province, China.
Mei-Hao Gao *Pediatric Department, The Hong Kong University of Shenzhen Hospital, Shenzhen, Guangdong Province, China.
Yi-Jiao MaDivision of Pediatric Nephrology, Shenzhen Children's Hospital, Shenzhen, Guangdong Province, China.
Shi-Lei JiaDivision of Pediatric Nephrology, Shenzhen Children's Hospital, Shenzhen, Guangdong Province, China.
Xiao-Jie GaoDivision of Pediatric Nephrology, Shenzhen Children's Hospital, Shenzhen, Guangdong Province, China. gxj3345@163.com.
Jun LiDivision of Pediatric Nephrology, Shenzhen Children's Hospital, Shenzhen, Guangdong Province, China. 18676597552@163.com.ORCID http://orcid.org/0000-0001-7856-4402

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPediatric renal abscess is an uncommon but serious complication of urinary tract infection, often characterized by nonspecific symptoms and delayed diagnosis.

methodsWe retrospectively analyzed 69 children with radiologically confirmed renal abscesses treated between November 2012 and February 2024. Clinical characteristics, laboratory findings, imaging results, management, and outcomes were evaluated across different age groups.

resultsThe median patient age was 24.0 months (IQR 7.3-66.8). There was a marked male predominance in infants (1-24 months) versus a female predominance in children over 60 months, with fever present in 98.6% of cases. Diagnosis was confirmed in all patients by contrast-enhanced CT or MRI, which revealed a mean attenuation difference of 28.8 ± 8.0 HU between the abscess and renal parenchyma; ultrasound sensitivity was 79.7%. Urine cultures were positive in 33.3% of cases, predominantly for Escherichia coli. Notably, vesicoureteral reflux was detected in 52.6% of evaluated patients. While surgical intervention was required in only 7.2% (5/69), these patients had a significantly higher rate of acute kidney injury compared to the conservative group (60% vs. 3.1%; P = 0.0018). The median hospital stay was 12.0 days (IQR 9.0-15.0) and was significantly prolonged in patients with left-sided or bilateral involvement (adjusted P = 0.032 and 0.033, respectively).

conclusionMost pediatric renal abscesses can be successfully managed conservatively. Vesicoureteral reflux is common, and acute kidney injury is markedly more frequent among children who require surgical treatment.

Indexed as

AbscessKidney DiseasesUrinary Tract InfectionsAcute Kidney InjuryAnti-Bacterial AgentsChildChild, PreschoolConservative TreatmentEscherichia coli InfectionsFemaleHumansInfantKidneyLength of StayMagnetic Resonance ImagingMaleAnti-Bacterial AgentsChildrenEnhanced CT/MRIRenal abscessVesicoureteral reflux

Identifiers

PMID41888477
PMCPMC13424581

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.