Evidence map›Paper›PMID 41888267›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026

Associations of Chiari-1 malformation and syringomyelia with osseous cervical spinal canal diameter in the pediatric spine.

Alexander T Yahanda, Devin W Kolmetzky, Vivek P Gupta, Jennifer M Strahle, Sean D McEvoy, Gabe Haller, Thanda Meehan, Brian A Kelly, Scott J Luhmann, Joshua S Shimony and 2 more

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexander T Yahanda *Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA. ayahanda@wustl.edu.
Devin W Kolmetzky *Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Vivek P GuptaDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Jennifer M StrahleDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Sean D McEvoyDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Gabe HallerDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Thanda MeehanDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Brian A KellyDepartment of Orthopedic Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Scott J LuhmannDepartment of Orthopedic Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Joshua S ShimonyDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
James C TornerDepartment of Neurological Surgery, School of Medicine, University of Iowa, Iowa City, IA, USA.
David D LimbrickDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examine the associations between cerebellar tonsillar ectopia and syrinx size on bony spinal canal diameter in pediatric patients to explore the impact of CM with or without SM on the developing spine.

methodsCohorts of patients with CM + SM, CM-only, and neither condition were compared. Anteroposterior (AP) syrinx diameter was measured at C2 (SX

results357 patients had CM + SM and 217 patients had CM-only. Both cohorts had larger SC

conclusionsPatients with CM ± SM experience significant increases in bony cervical spinal canal diameter during development. Syringes ≥ 3 mm with CM are associated with further canal dilation of the spinal canal at syrinx level. The degree of spinal canal dilation appears to be age- and sex-dependent.

Indexed as

Arnold-Chiari MalformationCervical VertebraeSpinal CanalSyringomyeliaAdolescentChildChild, PreschoolCohort StudiesFemaleHumansInfantMaleCervical spineChiari-1 malformationPediatric spineSpinal canal diameterSpinal canal dilationSpine developmentSyringomyelia

Identifiers

PMID41888267
PMCPMC13021709

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.