ArticleThe Laryngoscope2026
Quantifying Dehydration Effects of Porcine Vocal Fold Attenuation With Optical Coherence Tomography.
Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- In Reference to Quantifying Dehydration Effects of Porcine Vocal Fold Attenuation With Optical Coherence Tomography.The Laryngoscope · 2026Article
- In Response to Quantifying Dehydration Effects of Porcine Vocal Fold Attenuation With Optical Coherence Tomography.The Laryngoscope · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveThe purpose of this study is to use optical coherence tomography (OCT) to characterize the effect of dehydration on the optical attenuation coefficient of porcine vocal fold (VF) tissue. Assessing laryngeal hydration is clinically relevant for evaluating vocal function; however, no reliable noninvasive methods currently exist to quantify it.
methodsSix porcine larynges were bisected into 12 halves, yielding 12 VFs. Each specimen underwent serial dehydration using a vacuum oven to approximately 5%, 10%, and 15% mass loss, with OCT scans obtained at each interval using a 1300 nm wavelength system. Attenuation coefficients were extracted from OCT B-scans through custom MATLAB processing, and the relationship between tissue dehydration and attenuation was modeled using a linear mixed-effects model.
resultsAcross VFs, attenuation decreased by approximately 0.08 mm
conclusionsOCT-derived attenuation provides a quantitative, reproducible indicator of VF dehydration. The linear relationship between attenuation and tissue mass loss supports the feasibility of OCT as a noninvasive optical biomarker of VF hydration. Future multi-wavelength and in vivo studies will be critical to translate this approach into clinical monitoring of VF hydration, edema, and lesion formation. LEVEL OF EVIDENCE: NA.
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