Evidence map›Paper›PMID 41887735›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2026

Delta-like Ligand 3-Directed

Tran T Hoang, David Bauer, Aidan Ingham, Ileana C Miranda, Lukas M Carter, Alexa Michel, Roberto De Gregorio, Juliana Welk, Hong Zhong, John T Poirier and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tran T HoangDepartment of Pharmacology, Weill Cornell Graduate School of Medical Sciences, New York, New York.
David BauerProgram in Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York.
Aidan InghamProgram in Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York.
Ileana C MirandaLaboratory of Comparative Pathology, Memorial Sloan Kettering Cancer Center, Weill Cornell Medicine, and The Rockefeller University, New York, New York.
Lukas M CarterDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York.
Alexa MichelProgram in Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York.
Roberto De GregorioProgram in Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York.
Juliana WelkDepartment of Pharmacology, Weill Cornell Graduate School of Medical Sciences, New York, New York.
Hong ZhongDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
John T PoirierPerlmutter Cancer Center, New York University Langone Health, New York, New York; and.
Michael J MorrisDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Lisa BodeiDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Charles M RudinDepartment of Pharmacology, Weill Cornell Graduate School of Medical Sciences, New York, New York.
Salomon TendlerProgram in Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York.
Jason S LewisDepartment of Pharmacology, Weill Cornell Graduate School of Medical Sciences, New York, New York; lewisj2@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Elisa de Stanchina · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

This work evaluated the in vivo performance of an anti-delta-like ligand 3 (DLL3) monoclonal antibody, TDI-Y-010, covalently linked to the MACROPA-derived chelator (mcp) for

Indexed as

ActiniumAntibodies, MonoclonalLung NeoplasmsNeuroendocrine TumorsProstatic NeoplasmsRadioimmunotherapyAnimalsCell Line, TumorFemaleHumansIntracellular Signaling Peptides and ProteinsMaleMembrane ProteinsMiceMice, NudeTissue DistributionActiniumActinium-225Antibodies, MonoclonalDLL3 protein, humanIntracellular Signaling Peptides and ProteinsMembrane Proteins225AcDLL3neuroendocrine cancerradioimmunotherapyradionuclide therapy

Identifiers

PMID41887735
PMCPMC13224881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.