Evidence map›Paper›PMID 41887665›Full record

Trial reportBMJ global health2026

A livelihood intervention improved nutritional, mental health and sexual health outcomes among HIV-affected adolescents in western Kenya: results from the

Sheri D Weiser, Lila Aziz Sheira, Pauline Wekesa, Jennifer Monroe Zakaras, Edward A Frongillo, Elly Weke, Jason M Nagata, Amy A Conroy, Marguerita Lightfoot, Torsten B Neilands and 4 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03741634 (Shamba Maisha), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03741634 nacompletednot on this map

Shamba Maisha: Assessing the Preliminary Effects of a Multisectoral Agricultural Intervention on the Sexual and Reproductive Health of HIV-affected Adolescent Girls in Western Kenya

TypeinterventionalSponsorUniversity of California, San FranciscoRan2018 to 2019Enrolled241ConditionsAdolescent Behavior, Sexual Behavior, Reproductive BehaviorArmsMulti-sectoral agricultural intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sheri D WeiserDepartment of Medicine, University of California San Francisco, San Francisco, California, USA Sheri.Weiser@ucsf.edu.ORCID 0000-0002-7807-4072
Lila Aziz SheiraDepartment of Nursing, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0002-1831-8506
Pauline WekesaCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Jennifer Monroe ZakarasDepartment of Medicine, University of California San Francisco, San Francisco, California, USA.
Edward A FrongilloArnold School of Public Health, University of South Carolina, Columbia, South Carolina, USA.ORCID 0000-0002-8265-9815
Elly WekeCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Jason M NagataDepartment of Pediatrics, University of California San Francisco, San Francisco, California, USA.
Amy A ConroyDepartment of Medicine, University of California San Francisco, San Francisco, California, USA.
Marguerita LightfootPortland State University School of Public Health, Portland, Oregon, USA.
Torsten B NeilandsDepartment of Medicine, University of California San Francisco, San Francisco, California, USA.
Lisa M ButlerDepartment of Public Health Sciences, Queen's University, Kingston, Ontario, Canada.ORCID 0000-0002-7772-4555
Elizabeth A BukusiCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Craig R CohenDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California San Francisco, San Francisco, California, USA.
Maricianah Atieno OnonoKenya Medical Research Institute, Nairobi, Kenya.ORCID 0000-0001-6847-8762

Funding

Agricultural intervention for food security and HIV healthoutcomes in KenyaR01MH107330 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COHEN, CRAIG R, WEISER, SHERI DAWN · 2015 to 2019
$4.7M
Sustainable Development for Improved HIV Health and Prevention in Kenya (SD4H-Kenya)D43TW011306 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BUKUSI, ELIZABETH ANNE, COHEN, CRAIG R · 2020 to 2024
$1.9M
Assessing the preliminary effects of a multisectoral agricultural intervention on the sexual and reproductive health of HIV-affected adolescent girlsR21HD095739 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WEISER, SHERI DAWN · 2018 to 2019
$399k
FIC NIH HHS D43 TW011306NICHD NIH HHS 1R21-HD095739NICHD NIH HHS R21 HD095739NIMH NIH HHS R01 MH107330NIMH NIH HHS R01-MH107330
6 · The paper itself

Abstract

introductionInterventions that address household-level factors, including food insecurity (FI) and poverty, may reduce HIV risk and improve sexual and reproductive health (SRH) among adolescent girls and young women (AGYW).

methodsThis cluster randomised controlled trial in Kenya assessed AGYW living in households of adults enrolled in

resultsThe study enrolled 241 AGYW-caregiver pairs (n=131 intervention). The median age of AGYW was 15 years old (IQR: 14-17 years old). At endline, AGYW in intervention households had less FI (OR: 0.45, 95% CI 0.21 to 0.97; p=0.04), lower depressive symptomatology (OR: 0.53; 95% CI 0.24 to 1.15, p=0.11) and no difference in unprotected sex (OR: 1.16; 95% CI 0.63 to 2.16; p=0.63) compared with those in control households. In the secondary analysis, intervention AGYW had higher body mass index (β: 1.25; SE: 0.32; p=0.002), fewer symptoms of depression (OR: 0.42; 95% CI 0.21 to 0.84; p=0.01) and anxiety (OR: 0.23, 95% CI 0.05 to 1.11; p=0.07), and less sexual intimate partner violence (IPV) (OR: 0.28; 95% CI 0.08 to 0.91; p=0.03) than control AGYW. Intervention arm caregivers had less FI than those in the control arm (OR: 0.05; 95% CI 0.0047 to 0.54; p=0.014).

conclusionsAn agricultural livelihood intervention among adults living with HIV improved FI, mental health and IPV outcomes among AGYW in their households. These findings will guide the scale-up of an agricultural livelihood intervention for HIV-affected households with AGYW in sub-Saharan Africa. TRIAL REGISTRATION NUMBER: NCT03741634.

Indexed as

HIV InfectionsMental HealthNutritional StatusSexual HealthAdolescentFemaleFood InsecurityHumansKenyaMalePovertyYoung AdultHIVIntervention studyKenyaNutritionRandomised control trial

Identifiers

PMID41887665
PMCPMC13034210

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.