Evidence map›Paper›PMID 41887572›Full record

ArticleJournal of food protection2026

Trends in a Persistent Strain of Multidrug-Resistant Salmonella Infantis (REPJFX01) in Humans and Chickens - United States, 2010-2023.

Laura Ford, Daniel Lowell Weller, Molly K Steele, Jovita H Haro, Zachary Ellison, Molly Leeper, Kelley Hise, Marisa Hast, Jessica C Chen, Jared L Reynolds and 2 more

Abstract read
In one paragraph

Article in Journal of food protection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Draft genome sequences of 188Microbiology resource announcements · 2026
    Article
  3. A spotlight on multidrug-resistantFrontiers in microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Laura FordDivision of Foodborne, Waterborne, and Environmental Diseases, CDC, Atlanta, GA, USA. Electronic address: qdz4@cdc.gov.
Daniel Lowell WellerDivision of Foodborne, Waterborne, and Environmental Diseases, CDC, Atlanta, GA, USA.
Molly K SteeleDivision of Foodborne, Waterborne, and Environmental Diseases, CDC, Atlanta, GA, USA.
Jovita H HaroFood Safety and Inspection Service, USDA, Washington, DC, USA.
Zachary EllisonDivision of Foodborne, Waterborne, and Environmental Diseases, CDC, Atlanta, GA, USA; ASRT, Inc., Smyrna, GA, USA.
Molly LeeperDivision of Foodborne, Waterborne, and Environmental Diseases, CDC, Atlanta, GA, USA.
Kelley HiseDivision of Foodborne, Waterborne, and Environmental Diseases, CDC, Atlanta, GA, USA.
Marisa HastDivision of Foodborne, Waterborne, and Environmental Diseases, CDC, Atlanta, GA, USA.
Jessica C ChenDivision of Foodborne, Waterborne, and Environmental Diseases, CDC, Atlanta, GA, USA.
Jared L ReynoldsDivision of Foodborne, Waterborne, and Environmental Diseases, CDC, Atlanta, GA, USA.
Laura A CooleyDivision of Foodborne, Waterborne, and Environmental Diseases, CDC, Atlanta, GA, USA.
Louise K Francois WatkinsDivision of Foodborne, Waterborne, and Environmental Diseases, CDC, Atlanta, GA, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Chicken is a major source of foodborne salmonellosis in the United States. The number of human illnesses and the prevalence in chicken of a multidrug-resistant strain of Salmonella enterica serotype Infantis called REPJFX01 have increased during the last decade. REPJFX01 isolates are often resistant to antibiotics used for treatment, including ampicillin, ceftriaxone, ciprofloxacin, and trimethoprim-sulfamethoxazole. Using data from the U.S. Centers for Disease Control and Prevention's PulseNet system and the U.S. Department of Agriculture's Food Safety and Inspection Service during 2003-2023, we examined trends in REPJFX01 isolation from humans and chicken carcasses to assess whether they coincide. We used penalized B-spline generalized additive models to quantify trends in human infection burden and REPJFX01 prevalence on chicken carcasses. We used a time-lagged rank-order cross-correlation to characterize the association between the two-time series. A significant, increasing annual trend in the incidence of human infections and chicken carcass prevalence began in 2016. A 0-year lag on chicken carcass REPJFX01 prevalence maximized rank-order cross-correlation with REPJFX01 infection burden in humans. REPJFX01 trends in humans and chickens appear coincident (both occurring during the same time period), suggesting that chickens may be an important reservoir for REPJFX01. Efforts to prevent Salmonella contamination of chicken and strengthen safe handling and cooking of chicken should be prioritized.

Indexed as

ChickensDrug Resistance, Multiple, BacterialSalmonella entericaAnimalsAnti-Bacterial AgentsFood MicrobiologyHumansPrevalenceSalmonellaSalmonella Food PoisoningUnited StatesAnti-Bacterial AgentsChickenFoodborne diseasesIncidenceREP strainSalmonella entericaserovar Infantis

Identifiers

PMID41887572
PMCPMC13456058

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.