Evidence map›Paper›PMID 41887197›Full record

ArticleChemSusChem2026

Structured Electrodes Enable High-Rate and Selective Electrochemical Nicotinamide Adenine Dinucleotide Regeneration for Biocatalysis.

Jonas Wolf, Roman Goy, Jonathan Alan Medlock, Julian Tobias Kleinhaus, Kevinjeorjios Pellumbi, Leon Wickert, Daniel Siegmund, Ulf-Peter Apfel

Abstract read
In one paragraph

Article in ChemSusChem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jonas WolfDepartment Power-To-Chemicals, Fraunhofer Institute for Environmental, Safety and Energy Technology UMSICHT, Oberhausen, Germany.
Roman GoyDSM-Firmenich, Kaiseraugst, Switzerland.
Jonathan Alan MedlockDSM-Firmenich, Kaiseraugst, Switzerland.
Julian Tobias KleinhausActivation of Small Molecules, Technical Electrochemistry, Ruhr University Bochum, Bochum, Germany.ORCID 0000-0002-0901-4789
Kevinjeorjios PellumbiDepartment Power-To-Chemicals, Fraunhofer Institute for Environmental, Safety and Energy Technology UMSICHT, Oberhausen, Germany.ORCID 0000-0002-5313-5799
Leon WickertActivation of Small Molecules, Technical Electrochemistry, Ruhr University Bochum, Bochum, Germany.ORCID 0009-0005-6016-1492
Daniel SiegmundDepartment Power-To-Chemicals, Fraunhofer Institute for Environmental, Safety and Energy Technology UMSICHT, Oberhausen, Germany.ORCID 0000-0003-2476-8965
Ulf-Peter ApfelDepartment Power-To-Chemicals, Fraunhofer Institute for Environmental, Safety and Energy Technology UMSICHT, Oberhausen, Germany.ORCID 0000-0002-1577-2420

Funding

Bundesministerium für Forschung, Technologie und Raumfahrt 031B1403ABundesministerium für Forschung, Technologie und Raumfahrt 03XP0421Deutsche Forschungsgemeinschaft AP242/22-1Deutsche Forschungsgemeinschaft AP242/23-1Deutsche Forschungsgemeinschaft EXC2033-390677874-RESOLVMinistry of Culture and Science of the German state of North Rhine-Westphalia "MAT4HY.NRW"(KP22-065-A)Studienstiftung des Deutschen Volkes
6 · The paper itself

Abstract

Direct electrochemical regeneration of nicotinamide adenine dinucleotide (NADH) presents a cost-effective and sustainable alternative to enzymatic recycling approaches, yet its industrial application has been hampered by low reaction rates and insufficient selectivity. In this study, we demonstrate the integration of electrochemical NADH regeneration into a zero-gap electrolyzer and systematically evaluate copper, silver, and titanium electrodes with respect to activity and selectivity toward 1,4-NADH. Titanium felt exhibits 100% selectivity for this reaction at a rate of 194 µmol h

Indexed as

BiocatalysisNADElectrochemistryElectrodesTitaniumNADTitaniumbiological cofactorselectrochemistryenzymatic catalysishydrogenationzero‐gap electrolysis

Identifiers

PMID41887197
PMCPMC13021300

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.