Evidence map›Paper›PMID 41887016›Full record

ArticleJACC. Advances2026

Health Literacy Interventions and Outcomes in Patients WithAtrial Fibrillation: A Systematic Review and Meta-Analysis.

Timothy J H Lathlean, Don Kieu, Kyle B Franke, Nathan O'Callaghan, Mark A Boyd, Rajiv Mahajan

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Article in JACC. Advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Timothy J H LathleanSchool of Medicine, College of Health, Adelaide University, Adelaide, South Australia, Australia; South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia; The Commonwealth Science and Industrial Research Organisation (CSIRO), Precision Health, Adelaide, Australia.
Don KieuSchool of Medicine, College of Health, Adelaide University, Adelaide, South Australia, Australia.
Kyle B FrankeSchool of Medicine, College of Health, Adelaide University, Adelaide, South Australia, Australia.
Nathan O'CallaghanSouth Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia; The Commonwealth Science and Industrial Research Organisation (CSIRO), Precision Health, Adelaide, Australia.
Mark A BoydSchool of Medicine, College of Health, Adelaide University, Adelaide, South Australia, Australia; South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia; Lyell McEwin Hospital, Northern Adelaide Local Health Network, Adelaide, South Australia, Australia.
Rajiv MahajanSchool of Medicine, College of Health, Adelaide University, Adelaide, South Australia, Australia; South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia; Lyell McEwin Hospital, Northern Adelaide Local Health Network, Adelaide, South Australia, Australia. Electronic address: rajiv.mahajan@adelaide.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealth literacy interventions have the potential to improve health outcomes in patients with atrial fibrillation (AF).

objectivesThis meta-analysis aimed to investigate the relationship between health literacy interventions and patient knowledge, patient action, and clinical outcomes in patients with AF.

methodsMEDLINE, EMBASE, Web of Science, CINAHL, Emcare, Cochrane Library, and Google Scholar were searched for studies reporting health literacy interventions in patients with AF till August 30, 2024.

resultsOf the 3,889 records identified, 53 studies were included in the final review. There is a shift in the trajectory of health literacy interventions from face-to-face to digital delivery. A large positive effect (n = 12; Hedges' g = 0.95 [0.55-1.35]) was observed for knowledge outcomes, with benefits for both digital and face-to-face interventions and uncertainty of sustained improvement beyond 12 months. There was an improvement in patient action outcomes (n = 11; Hedges' g = 0.54 [0.16-0.92]), driven by a moderate-sized effect for treatment adherence (n = 6; Hedges' g = 0.61 [0.19-1.03]) but an uncertain effect on self-efficacy. A small number of studies incorporated interventions, such as rhythm monitoring and reminder texts for patients, as well as software for doctors, to improve adherence to recommended guidelines. For clinical outcomes, health literacy interventions were associated with lower emergency department visits (n = 4; OR: 0.69 [0.48-0.98]), hospitalization (n = 14; OR: 0.56 [0.44-0.73]), and mortality (n = 16; OR: 0.64 [0.49-0.82]).

conclusionsHealth literacy interventions are demonstrating a trajectory toward a digital mode, extending beyond patient education, and are associated with gains in AF knowledge, treatment adherence, and improved survival.

Indexed as

AF knowledgeatrial fibrillationhealth literacyhospitalizationquality of lifeself-efficacy

Identifiers

PMID41887016
PMCPMC13053986

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.