Evidence map›Paper›PMID 41886630›Full record

ArticleJournal of natural products2026

AI-Assisted Isolation of Bioactive Dipyrimicins from

Christine Mae F Ancajas, Isra Shuster, Allison S Walker

Abstract read
In one paragraph

Article in Journal of natural products, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Christine Mae F AncajasDepartment of Chemistry, Vanderbilt University, 1234 Stevenson Center Lane, Nashville, Tennessee 37240, United States.ORCID 0000-0001-5697-2202
Isra ShusterDepartment of Chemistry, Vanderbilt University, 1234 Stevenson Center Lane, Nashville, Tennessee 37240, United States.ORCID 0009-0007-8746-8747
Allison S WalkerDepartment of Chemistry, Vanderbilt University, 1234 Stevenson Center Lane, Nashville, Tennessee 37240, United States.ORCID 0000-0001-5666-7232

Funding

Machine learning approaches for the discovery, repurposing, and optimization of natural products with therapeutic potential - Supplement to support grad training of Adrian RussR35GM146987 · NIGMS · VANDERBILT UNIVERSITY · PI Allison Sara Walker · 2022 to 2026
$2.4M
NIGMS NIH HHS R35 GM146987
6 · The paper itself

Abstract

One of the major challenges in natural product discovery is the prioritization of compounds with useful activities from microbial sources. Here, we utilize a machine learning model that predicts the antibacterial activity of a natural product from its biosynthetic gene cluster (BGC) into our genome mining pipeline. Using this approach, we prioritized the strain

Indexed as

Artificial IntelligenceMultigene Family2,2'-DipyridylAmycolatopsisAnti-Bacterial AgentsBiological ProductsMachine Learning2,2'-DipyridylAnti-Bacterial AgentsBiological Products

Identifiers

PMID41886630
PMCPMC13122635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.