ReviewAAPS PharmSciTech2026
Unveiling the Potential of Plant-derived Exosomes: A Comprehensive Review.
Review in AAPS PharmSciTech, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extracellular vesicles, including exosomes, are naturally produced by various cell types both in vivo and in vitro. These nanovesicles, composed of a lipid bilayer, proteins, and RNAs, play a pivotal role in intercellular communication. Their inherent characteristics make them promising candidates as diagnostic tools and therapeutics for conditions like cancer. Recently, plant-derived exosomes (PDEs) have gained attention as a viable alternative to mammalian exosomes due to their ability to overcome several technical limitations. This review explores the origins and isolation methods of PDEs, evaluating their structural and biochemical properties that enable them to function as nanocarriers. The review covers various methods employed in isolating and purifying PDEs, as well as the interdisciplinary approaches that may enhance the efficiency, reproducibility, and scalability of these techniques. PDEs exhibit anticancer and antioxidant properties and show great therapeutic potential in drug delivery due to their physiological, chemical, and biological characteristics. They are capable of delivering various medications with high reproducibility. Despite these advantages, the current isolation and separation techniques for PDEs remain time-consuming and technically challenging, sometimes posing safety risks. While PDEs represent a promising avenue for drug delivery systems due to their inherent metabolic properties and therapeutic effects, several challenges remain. There is a need to refine isolation and drug-loading techniques, potentially through interdisciplinary strategies involving biological sciences. Therefore, continued research is essential to develop safer and more efficient drug delivery platforms using PDEs.
Indexed as
Identifiers
41886225What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.