ArticleJournal of autism and developmental disorders2026
Emergency Department Care for Patients With Prader-Willi Syndrome: A 2019-2021 National Emergency Department Sample Analysis.
Article in Journal of autism and developmental disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
purposePrader-Willi syndrome (PWS) is a rare genetic disorder with complex medical and psychiatric manifestations that may necessitate emergency department (ED) care. This study characterizes ED presentations among patients with PWS using a nationally representative cohort of ED presentations in the United States.
methodsThe National Emergency Department Sample (NEDS) was queried for patients with a coded diagnosis of PWS from Oct 2019 through Dec 2021. ED presentations for patients with PWS were matched to 5 non-PWS presentations based on age, sex, year, and hospital characteristics.
resultsOver 27 months there were 8,100 (95% CI 6,759 to 9,441) ED presentations for patients with PWS, or approximately 1 in 35,000 overall ED presentations. PWS patients were predominantly young (median age: 23 years), with notable comorbidities including septicemia, respiratory failure, and psychiatric conditions such as agitation and impulse-control disorders. Compared to matched control patients, PWS patients had higher odds of hospital admission (43.3% vs. 11.9%; adjusted odds ratio [aOR]: 6.0) and death (1.6% vs. 0.1%; aOR: 11.2) during their hospital encounter.
conclusionsIndividuals with PWS present to the emergency department with numerous medical and psychiatric complexities resulting in greater clinical complexity and mortality than matched control presentations. The rarity of PWS in the ED likely implies limited provider familiarity, which may exacerbate challenges in care delivery. These findings emphasize the need for increased awareness and education regarding PWS among emergency care providers and identify best practices for addressing the acute care needs of this vulnerable population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.