Evidence map›Paper›PMID 41885880›Full record

ArticleExperimental and clinical psychopharmacology2026

Neurobehavioral differences in value-based decision making between people with cocaine use disorder and controls.

Joshua A Lile, Preston T Tolbert, Thomas P Shellenberg, William W Stoops, Justin C Strickland, Joshua S Beckmann, Michael J Wesley

Abstract read
In one paragraph

Article in Experimental and clinical psychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joshua A LileDepartment of Behavioral Science, University of Kentucky, College of Medicine.ORCID 0000-0002-6237-8557
Preston T TolbertDepartment of Biostatistics, University of Kentucky, College of Public Health.ORCID 0000-0002-8451-8848
Thomas P ShellenbergDepartment of Behavioral Science, University of Kentucky, College of Medicine.
William W StoopsDepartment of Behavioral Science, University of Kentucky, College of Medicine.
Justin C StricklandDepartment of Psychiatry, University of Maryland School of Medicine.
Joshua S BeckmannDepartment of Psychology, University of Kentucky, College of Arts and Sciences.
Michael J WesleyDepartment of Behavioral Science, University of Kentucky, College of Medicine.

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
Research Training in Drug Abuse BehaviorT32DA035200 · NIDA · UNIVERSITY OF KENTUCKY · PI CRAIG R RUSH, William Walton Stoops · 2013 to 2026
$4.4M
A translational determination of the mechanisms of maladaptive choice in cocaine use disorderR01DA045023 · NIDA · UNIVERSITY OF KENTUCKY · PI BECKMANN, JOSHUA, LILE, JOSHUA ANTHONY · 2018 to 2022
$3.0M
Neural Mechanisms of Cannabinoid-Impaired Decision-Making in Emerging AdultsK01DA043652 · NIDA · UNIVERSITY OF KENTUCKY · PI WESLEY, MICHAEL J · 2018 to 2022
$792k
National Institutes of Health; National Institute on Drug AbuseNCATS NIH HHS UL1 TR001998NIDA NIH HHS K01 DA043652NIDA NIH HHS R01 DA045023NIDA NIH HHS T32 DA035200
6 · The paper itself

Abstract

Decision making occurs in dynamic contexts in which the individual and reward attributes change, requiring that predicted reward values of options be updated continually and applied to future choices to maximize reward. Value processing relies on corticostriatal dopamine, which is dysregulated in people with cocaine use disorder (pwCocUD), but whether these individuals differ in value-based decision making has only recently been considered. A probabilistic concurrent monetary choice task with reversals, reinforcement learning modeling, and functional magnetic resonance imaging were used to assess value-based decision making in nontreatment-seeking pwCocUD and matched controls (

Indexed as

Cocaine-Related DisordersDecision MakingAdultBrainChoice BehaviorFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedReinforcement Machine LearningReinforcement, PsychologyReward

Identifiers

PMID41885880
PMCPMC13025760

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.