Evidence map›Paper›PMID 41885736›Full record

ArticlePhysiological reports2026

Changes in intramuscular blood flow and muscle deoxygenation at different parts of the vastus lateralis during intermittent isometric knee extension in young adult males.

Kazuma Izumi, Keisho Katayama, Yutaka Kano, Noriko Tanaka, Hiroshi Akima

Abstract read
In one paragraph

Article in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kazuma IzumiGraduate School of Education and Human Development, Nagoya University, Nagoya, Aichi, Japan.ORCID 0009-0008-5197-1006
Keisho KatayamaResearch Center of Health, Physical Fitness and Sports, Nagoya University, Nagoya, Aichi, Japan.ORCID 0000-0001-7245-3496
Yutaka KanoDepartment of Engineering Science, Bioscience and Technology Program, University of Electro-Communications, Chofu, Tokyo, Japan.ORCID 0000-0003-0913-9714
Noriko TanakaGraduate School of Education and Human Development, Nagoya University, Nagoya, Aichi, Japan.ORCID 0000-0002-9413-2754
Hiroshi AkimaGraduate School of Education and Human Development, Nagoya University, Nagoya, Aichi, Japan.ORCID 0000-0002-2048-7210

Funding

MEXT | Japan Science and Technology Agency (JST) JPMJSP2125Ministry of Education, Culture, Sports, Science and Technology (MEXT) 22K19728
6 · The paper itself

Abstract

Regional differences in oxygen supply-demand balance in active muscles may be related to exercise tolerance. However, the dynamics of oxygen supply-demand balance and its regional differences within active muscles have not been clarified. The purpose of this study was to evaluate regional differences in the patterns of change in the relationship between intramuscular blood flow and muscle deoxygenation along the vastus lateralis length during submaximal isometric knee extension. Thirteen healthy young males (19.4 ± 0.9 years) performed intermittent (5-s contraction and 5-s relaxation) isometric knee extension at 50% of maximal voluntary contraction for 18 contractions. Intramuscular blood flow and deoxy-[hemoglobin+myoglobin] (deoxy-[Hb+Mb]) were simultaneously measured using power Doppler ultrasonography and near-infrared spectroscopy, respectively, at the proximal, middle and distal sites of the vastus lateralis. The ratio of intramuscular blood flow to deoxy-[Hb+Mb] (intramuscular blood flow/deoxy-[Hb+Mb]) was calculated. There was no significant interaction (measurement site × time) for intramuscular blood flow/deoxy-[Hb+Mb] (proximal; 256 ± 138 a.u., middle; 384 ± 228 a.u., distal; 291 ± 197 a.u., F = 1.683, p = 0.076). These results suggest that the balance between oxygen supply and demand is uniformly regulated in the vastus lateralis along its length during intermittent submaximal isometric knee extension.

Indexed as

Isometric ContractionOxygenOxygen ConsumptionQuadriceps MuscleRegional Blood FlowHemoglobinsHumansKneeMaleSpectroscopy, Near-InfraredUltrasonography, DopplerYoung AdultHemoglobinsOxygenintramuscular blood flowmuscle deoxygenationnear‐infrared spectroscopypower Doppler ultrasonographyregional difference

Identifiers

PMID41885736
PMCPMC13097460

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.