Evidence map›Paper›PMID 41885428›Full record

ArticlemSphere2026

A heterologous marker-free selection approach for CRISPR/Cas9-based gene editing in the malaria parasite

Eilidh Carrington, Daniel Ballmer, Igor Niederwieser, Basil T Thommen, Nicolas M B Brancucci, Till S Voss

Abstract read
In one paragraph

Article in mSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eilidh CarringtonDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.ORCID 0000-0001-7419-0810
Daniel BallmerDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.ORCID 0000-0002-1966-0960
Igor NiederwieserDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
Basil T ThommenDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
Nicolas M B BrancucciDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
Till S VossDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.ORCID 0000-0002-1464-4988

Funding

European Molecular Biology Organization ALTF 920-2024Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 310030_184785,310030_220001Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 310030_200683
6 · The paper itself

Abstract

CRISPR/Cas9-based gene editing of the malaria parasite

Indexed as

CRISPR-Cas SystemsGene EditingPlasmodium falciparumAntimalarialsDrug ResistanceHumansMultienzyme ComplexesProtozoan ProteinsPyrimethamineTetrahydrofolate DehydrogenaseThymidylate SynthaseAntimalarialsMultienzyme ComplexesProtozoan ProteinsPyrimethamineTetrahydrofolate DehydrogenaseThymidylate Synthasethymidylate synthase-dihydrofolate reductaseCRISPR/Cas9malariaPlasmodium falciparum

Identifiers

PMID41885428
PMCPMC13123713

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.