Evidence map›Paper›PMID 41885138›Full record

ArticleClinical endocrinology2026

Transient Hyperparathyroidism and Severe Intrauterine Osteopenia Linked to Novel Homozygous TRPV6 Deletion.

Teodora Grigore, Quinty Leusink, Femke Latta, Bram van der Eerden, Paul de Laat, Danielle van der Kaay, Joost Hoenderop

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Teodora GrigoreDepartment of Medical BioSciences, Radboud Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, the Netherlands.
Quinty LeusinkDepartment of Medical BioSciences, Radboud Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, the Netherlands.
Femke LattaDepartment of Medical BioSciences, Radboud Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, the Netherlands.
Bram van der EerdenDepartment of Internal Medicine, Erasmus MC, Erasmus University Medical Center, Rotterdam, the Netherlands.
Paul de LaatDepartment of Pediatrics, Franciscus Gasthuis, Rotterdam, the Netherlands.
Danielle van der KaayDepartment of Pediatrics, Division of Endocrinology, Erasmus MC, Erasmus University Medical Center, Rotterdam, the Netherlands.
Joost HoenderopDepartment of Medical BioSciences, Radboud Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, the Netherlands.ORCID https://orcid.org/0000-0002-1816-8544

Funding

Radboud Institute for Molecular Life Sciences
6 · The paper itself

Abstract

contextPlacental calcium (Ca PATIENT MEASUREMENTS: The neonate was born with skeletal abnormalities, increased umbilical cord PTH levels (75 pmol/L) and normal total Ca

results

conclusionsThese findings indicate that the TRPV6-p.Arg492* mutation affects maternal-foetal Ca

Indexed as

Bone Diseases, MetabolicCalcium ChannelsHyperparathyroidismTRPV Cation ChannelsCalciumFemaleHomozygoteHumansInfant, NewbornMutationPregnancyCalciumCalcium ChannelsTRPV6 protein, humanTRPV Cation Channelsbone abnormalitieshyperparathyroidismmaternal‐foetal Ca2+ transportmutationosteopeniaplacentaTRPV6

Identifiers

PMID41885138
PMCPMC13326983

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.