Evidence map›Paper›PMID 41885084›Full record

ArticleInfection control and hospital epidemiology2026

Are high residual chlorhexidine skin concentrations associated with improved clinical outcomes? Lessons from the CLEAR trial.

Roya Khoja, Tabitha D Catuna, Gabrielle M Gussin, Kevin Nguyen, Raveena D Singh, Mary K Hayden, Loren G Miller, Susan S Huang

Abstract read
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In one paragraph

Article in Infection control and hospital epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Roya KhojaDivision of Infectious Diseases, University of California Irvine School of Medicinehttps://ror.org/04gyf1771, Irvine, USA.
Tabitha D CatunaDivision of Infectious Diseases, University of California Irvine School of Medicinehttps://ror.org/04gyf1771, Irvine, USA.
Gabrielle M GussinDivision of Infectious Diseases, University of California Irvine School of Medicinehttps://ror.org/04gyf1771, Irvine, USA.ORCID https://orcid.org/0000-0001-8051-7613
Kevin NguyenDivision of Infectious Diseases, University of California Irvine School of Medicinehttps://ror.org/04gyf1771, Irvine, USA.
Raveena D SinghDivision of Infectious Diseases, University of California Irvine School of Medicinehttps://ror.org/04gyf1771, Irvine, USA.
Mary K HaydenDivision of Infectious Diseases, Rush University Medical Center, Chicago, USA.
Loren G MillerDivision of Infectious Diseases, Lundquist Institute for Biomedical Innovation at Harbor- UCLA Medical Center, USA.ORCID https://orcid.org/0000-0003-0487-1711
Susan S HuangDivision of Infectious Diseases, University of California Irvine School of Medicinehttps://ror.org/04gyf1771, Irvine, USA.ORCID https://orcid.org/0000-0001-6748-3447

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Residual chlorhexidine gluconate (CHG) skin concentrations are thought to improve disease prevention. In the Changing Lives by Eradicating Antibiotic Resistance (CLEAR) trial, posthospitalization decolonization of MRSA carriers reduced MRSA infection and all-cause infection, but higher residual CHG concentrations did not improve outcomes. CHG concentration may indicate bathing quality, but high residual concentrations may not be necessary for benefit.

Identifiers

PMID41885084
PMCPMC13040246

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.