ArticleThe Australian & New Zealand journal of obstetrics & gynaecology2026
Identifying Priority Outcomes for Mothers and Babies in Pregnancies With Preterm Pre-Labour Rupture of Membranes for Future Clinical Trials.
Article in The Australian & New Zealand journal of obstetrics & gynaecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Preterm pre-labour rupture of membranes (PPROM) is associated with neonatal and maternal morbidity and mortality. Maternal prophylactic antibiotic therapy after PPROM improves outcomes but there is limited evidence to guide the optimal antibiotic regimen. This study surveyed 45 women with PPROM to understand consumer priorities for care, maternal and neonatal outcomes; and inform future PPROM clinical trial design. The highest priorities were prolonging gestation, avoiding brain injury, improving neonatal survival and good childhood respiratory health. Seventy-nine percent of respondents would consider clinical trial participation. Identifying consumer priorities will support both trial design and improved clinical care.
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