Evidence map›Paper›PMID 41884866›Full record

ArticleImaging neuroscience (Cambridge, Mass.)

A meta-analysis of neural systems underlying delay discounting: Implications for transdiagnostic research.

Nikhil V Lakhani, Min K Souther, Bema Boateng, Joseph W Kable

Abstract read
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nikhil V LakhaniDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, United States.ORCID https://orcid.org/0000-0002-9081-1514
Min K SoutherDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, United States.
Bema BoatengDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, United States.
Joseph W KableDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, United States.ORCID https://orcid.org/0000-0001-6495-9040

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delay discounting is a promising paradigm for transdiagnostic research because both excessive and insufficient tendency to discount future rewards have been reported across diagnoses. Because delay discounting involves multiple neurocognitive functions, researchers have used many strategies to characterize brain activity during delay discounting. However, which of these analytic approaches yield truly robust and replicable findings remains unclear. To this end, we conducted a meta-analysis of 80 fMRI studies of delay discounting, testing which statistical contrasts give rise to reliable effects across studies. Despite being a widely used analytic approach, comparing impulsive and patient choices did not reliably yield the expected effects. Instead, subjective value contrasts reliably engaged the valuation network, and task versus baseline and choice difficulty contrasts reliably engaged regions in the frontoparietal and salience networks. We strongly recommend that future neuroimaging studies of delay discounting use these analytic approaches shown to reliably identify specific networks. In addition, we provide all cluster maps from our meta-analysis for use as a priori regions of interest for future experiments.

Indexed as

delay discountingfMRIintertemporal choicemeta-analysisMKDA

Identifiers

PMID41884866
PMCPMC13010365

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.