Evidence map›Paper›PMID 41884625›Full record

ReviewJID innovations : skin science from molecules to population health2026

Autoantibodies as biomarkers of cancer risk in dermatomyositis.

Christina E Bax, Livia Casciola-Rosen, David Fiorentino

Abstract readReview
In one paragraph

Review in JID innovations : skin science from molecules to population health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christina E BaxDepartment of Dermatology, Stanford University School of Medicine, Redwood City, California, USA.
Livia Casciola-RosenDivision of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
David FiorentinoDepartment of Dermatology, Stanford University School of Medicine, Redwood City, California, USA.

Funding

Interrogating the pathophysiological mechanisms of constipation in patients with systemic sclerosisR01AR081382 · NIAMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Jiande Chen, Zsuzsanna Hortobagyi McMahan · 2023 to 2026
$2.4M
NIAMS NIH HHS R01 AR081382
6 · The paper itself

Abstract

Dermatomyositis (DM) is a cardinal example of an autoimmune rheumatic disease associated with an increased risk of cancer. Research over the past 2 decades highlights that specific DM autoantibodies are associated with overall risk of cancer emergence, with recent research identifying co-occurring "add-on" autoantibodies that appear to attenuate malignancy risk. Although the mechanism of this association remains unclear, a leading hypothesis is cancer-induced autoimmunity in which physiologic cancer immunosurveillance leads to autoimmune disease in the appropriate host. This review synthesizes our current understanding of autoantibodies and DM-associated malignancy with a focus on helping to individualize cancer risk stratification and allow selection of the appropriate aggressive and timely cancer screening modality.

Indexed as

AutoimmunityCancerDermatomyositisMyositis-specific antibodiesParaneoplastic conditions

Identifiers

PMID41884625
PMCPMC13011210

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.