Evidence map›Paper›PMID 41884598›Full record

ArticleBrain communications2026

Distinct neuroinflammatory profiles in progressive supranuclear palsy associated with

Shelley L Forrest, Sarah S Zaheer, Ain Kim, Hidetomo Tanaka, Helen Chasiotis, Jun Li, Susan H Fox, Jinguo Wang, M Carmela Tartaglia, Anthony E Lang and 1 more

Abstract read
In one paragraph

Article in Brain communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Neuroinflammation and Tauopathies.Molecular biology reports · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shelley L ForrestTanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario M5T 0S8, Canada.
Sarah S ZaheerRossy Centre for PSP, Toronto Western Hospital, Toronto, Ontario M5T 2S8, Canada.
Ain KimTanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario M5T 0S8, Canada.
Hidetomo TanakaTanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario M5T 0S8, Canada.
Helen ChasiotisTanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario M5T 0S8, Canada.
Jun LiTanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario M5T 0S8, Canada.
Susan H FoxRossy Centre for PSP, Toronto Western Hospital, Toronto, Ontario M5T 2S8, Canada.
Jinguo WangLaboratory Medicine Program, University Health Network, Toronto, Ontario M5G 2C4, Canada.
M Carmela TartagliaTanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario M5T 0S8, Canada.
Anthony E LangTanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario M5T 0S8, Canada.
Gabor G KovacsTanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario M5T 0S8, Canada.ORCID https://orcid.org/0000-0003-3841-5511

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive supranuclear palsy is a neurodegenerative four-repeat tauopathy characterized by atypical parkinsonism and cognitive behavioural changes and a relatively uniform neuropathology. Building on prior identification of rare

Indexed as

cytotoxic T cellsHLAmachine learningmicrogliaprogressive supranuclear palsy

Identifiers

PMID41884598
PMCPMC13012215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.