Evidence map›Paper›PMID 41884487›Full record

ReviewDrug design, development and therapy2026

Properties of Approved Antitumour Chinese Herbal Medicines: Integrating Evidence and Tradition.

Linlin Qi, Shushu Qian, Ling Wang, Zhixu Liu, Jiaxin Jiang, Chunmei Liu, Yang Pan, Bo Wang, Xuan Han, Jing Chen

Abstract readReview
In one paragraph

Review in Drug design, development and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Linlin Qi *National Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China.ORCID 0009-0000-5816-8402
Shushu Qian *Department of Rehabilitation Medicine, Center for Rehabilitation Medicine, Rehabilitation & Sports Medicine Research Institute of Zhejiang Province, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, People's Republic of China.
Ling Wang *National Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China.
Zhixu LiuNational Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China.
Jiaxin JiangNational Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China.
Chunmei LiuCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China.
Yang PanCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China.
Bo WangDepartment of Biopharmacy, China Pharmaceutical University, Nanjing, People's Republic of China.
Xuan HanNational Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China.
Jing ChenNational Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China.ORCID 0000-0002-2681-0349

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The properties and meridian affinities of Chinese herbal medicine are closely associated with their therapeutic efficacy. This review focuses on approved antitumour Chinese medicines listed in the Pharmacopoeia of the People's Republic of China (2020 Edition, Volume I), highlighting their key components. Statistical methods were used to analyse the properties, flavours and channel tropisms of antitumour traditional Chinese medicine (TCM), including both proprietary formulations and commercially available individual herbs. Distinctive patterns were identified by comparing herb profiles with contemporary experimental studies on antitumour TCM. Analysis revealed that bitter-cold herbs represented the highest proportion of antitumour TCM, with most showing tropism towards the liver channel. These findings provide a reference framework for antitumour drug development, indicating that bitter-cold herbs merit priority as candidate ingredients.

Indexed as

Antineoplastic Agents, PhytogenicDrugs, Chinese HerbalMedicine, Chinese TraditionalNeoplasmsAnimalsDrug ApprovalHumansAntineoplastic Agents, PhytogenicDrugs, Chinese Herbalantitumour traditional chinese medicinechannel tropismflavoursproperties

Identifiers

PMID41884487
PMCPMC13012539

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.