Evidence map›Paper›PMID 41884385›Full record

ReviewClinical, cosmetic and investigational dermatology2026

Cutaneous Symptoms of Cystic Fibrosis: A Narrative Review.

Michał Piątkiewicz, Barbara Olędzka, Anna Wołkowicz, Aneta Durmaj, Lidia Rudnicka

Abstract readReview
In one paragraph

Review in Clinical, cosmetic and investigational dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michał PiątkiewiczDepartment of Dermatology, Medical University of Warsaw, Warsaw, Poland.ORCID 0009-0005-5182-3407
Barbara OlędzkaDepartment of Dermatology, Medical University of Warsaw, Warsaw, Poland.ORCID 0009-0005-7785-8659
Anna WołkowiczCystic Fibrosis Centre, Paediatric Hospital, Dziekanów Leśny, Poland.ORCID 0000-0001-9500-9814
Aneta DurmajDepartment of Dermatology, Medical University of Warsaw, Warsaw, Poland.ORCID 0009-0009-5764-2817
Lidia RudnickaDepartment of Dermatology, Medical University of Warsaw, Warsaw, Poland.ORCID 0000-0002-8308-1023

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic fibrosis (CF) is caused by a mutation in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene and is characterized by recurrent pulmonary infections, fat malabsorption, and malnutrition. CF is associated with diverse dermatologic symptoms, including aquagenic palmoplantar keratoderma, nutrient deficiency dermatitis, and vasculitis. Sporadically, these manifestations may represent the initial symptoms of cystic fibrosis. Drug-induced skin reactions are commonly observed in patients with cystic fibrosis (pwCF) due to the chronic use of antibiotics. Therapy with CFTR modulators is considered the gold standard in the treatment of cystic fibrosis. Nevertheless, they are associated with numerous side effects, ranging from rash to Stevens-Johnson syndrome. Identifying the cutaneous manifestations of cystic fibrosis may support comprehensive care for patients. In this regard, dermatologists may play an important role in the management of associated skin complications.

Indexed as

antibiotic hypersensitivityaquagenic palmoplantar keratodermaCFTRcystic fibrosisnutrient deficiency dermatitisvasculitis

Identifiers

PMID41884385
PMCPMC13011965

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.