Evidence map›Paper›PMID 41884379›Full record

ArticleRSC advances2026

Integrated synthesis, antiproliferative potential, and

Sayed K Ramadan, Mariam S H Kazem, Mahmoud Kamal, Ahmed I Hashem, Hisham S M Abd-Rabboh, Wael S I Abou-Elmagd

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sayed K RamadanChemistry Department, Faculty of Science, Ain Shams University Cairo 11566 Egypt sayed.karam2008@sci.asu.edu.eg.ORCID https://orcid.org/0000-0003-2743-6544
Mariam S H KazemChemistry Department, Faculty of Science, Ain Shams University Cairo 11566 Egypt sayed.karam2008@sci.asu.edu.eg.
Mahmoud KamalEntomology Department, Faculty of Science, Ain Shams University Cairo 11566 Egypt.ORCID https://orcid.org/0000-0001-7447-0433
Ahmed I HashemChemistry Department, Faculty of Science, Ain Shams University Cairo 11566 Egypt sayed.karam2008@sci.asu.edu.eg.
Hisham S M Abd-RabbohChemistry Department, College of Science, King Khalid University P. O. Box 9004 Abha 62223 Saudi Arabia.ORCID https://orcid.org/0000-0002-5023-8135
Wael S I Abou-ElmagdChemistry Department, Faculty of Science, Ain Shams University Cairo 11566 Egypt sayed.karam2008@sci.asu.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Azofuranone was transformed into a series of pyrazole-based hydrazones with 71-79% yields through hydrazinolysis using hydrazine hydrate at room temperature followed by condensation with selected aromatic aldehydes in refluxing ethanol. The antiproliferative activity of the obtained derivatives was evaluated against MCF-7 (breast) and HCT-116 (colon) cancer cell lines using the MTT assay. Among the tested compounds, the chlorobenzylidene derivative (3a) exhibited the most pronounced cytotoxic activity (IC

Identifiers

PMID41884379
PMCPMC13010863

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.