Evidence map›Paper›PMID 41884368›Full record

ArticleRSC advances2026

Optimization of phenolics extraction and isolation from gymnosperms growing in Egypt using response surface methodology:

Asmaa M Akar, Nesrine M Hegazi, Ahmed Zayed, Souzan M Ibrahim

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Asmaa M AkarDepartment of Pharmacognosy, College of Pharmacy, Tanta University, El-Guish Street (Medical Campus) Tanta 31527 Egypt asmaa.akar@pharm.tanta.edu.eg ahmed.zayed1@pharm.tanta.edu.eg suzan.mostafa@pharm.tanta.edu.eg.
Nesrine M HegaziDepartment of Phytochemistry and Plant Systematics, Institute of Pharmaceutical Industries, National Research Centre Dokki Cairo 12622 Egypt nm.hegazi@nrc.sci.eg.ORCID https://orcid.org/0000-0003-4085-5938
Ahmed ZayedDepartment of Pharmacognosy, College of Pharmacy, Tanta University, El-Guish Street (Medical Campus) Tanta 31527 Egypt asmaa.akar@pharm.tanta.edu.eg ahmed.zayed1@pharm.tanta.edu.eg suzan.mostafa@pharm.tanta.edu.eg.ORCID https://orcid.org/0000-0001-5747-6972
Souzan M IbrahimDepartment of Pharmacognosy, College of Pharmacy, Tanta University, El-Guish Street (Medical Campus) Tanta 31527 Egypt asmaa.akar@pharm.tanta.edu.eg ahmed.zayed1@pharm.tanta.edu.eg suzan.mostafa@pharm.tanta.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gymnosperms are recognized as rich sources of phenolic constituents, particularly biflavonoids, which exhibit a wide range of biological activities, including antioxidant, anti-inflammatory, and anticancer effects. However, conventional extraction techniques such as maceration and Soxhlet extraction are often limited by prolonged extraction times and high solvent consumption. In this study, traditional extraction methods were systematically compared with modern techniques, namely microwave-assisted extraction (MAE) and ultrasound-assisted extraction (UAE), for the recovery of phenolic compounds from the leaves of

Identifiers

PMID41884368
PMCPMC13010161

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.